Results 111 to 120 of about 2,084,390 (260)

Mitochondrial glycerol 3-phosphate dehydrogenase deficiency exacerbates lipotoxic cardiomyopathy

iScience
Summary: Metabolic diseases such as obesity and diabetes induce lipotoxic cardiomyopathy, which is characterized by myocardial lipid accumulation, dysfunction, hypertrophy, fibrosis and mitochondrial dysfunction.
Hua Qu, Xiufei Liu, Jiaran Zhu, Niexia He, Qingshan He, Linlin Zhang, Yuren Wang, Xiaoli Gong, Xin Xiong, Jinbo Liu, Chuan Wang, Gangyi Yang, Qingwu Yang, Gang Luo, Zhiming Zhu, Yi Zheng, Hongting Zheng   +16 more
doaj   +1 more source

O-GlcNAcylation: cellular physiology and therapeutic target for human diseases. [PDF]

MedComm (2020), 2023
Ye L, Ding W, Xiao D, Jia Y, Zhao Z, Ao X, Wang J.   +6 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Small-Group Activity to Reinforce the Impact of Valvular Defects and Heart Failure on Cardiac Pressure-Volume Relationships

, 2018
Introduction An important topic in cardiac physiology is the relationship between changes in intracardiac pressures and volumes during the cardiac cycle.
Klabunde, Richard, Richard Klabunde, Hopper, Mari, Johnathan Tune, Tune, Johnathan, Mari Hopper   +5 more
core   +1 more source

Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease. [PDF]

Exp Biol Med (Maywood), 2023
Wang Q, Li M, Zeng N, Zhou Y, Yan J.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Physiology of the liver

, 2010
This RLO outlines the physiology of the ...
Vivian Rolfe
core  

Simulation in Exercise Science and Physiology—No Longer a Luxury but a Necessity

, 2020
The depreciation in placement opportunities has placed pressures on university academics for some time now. Today, the coalescence of this supply issue and the global health pandemic have forced the consideration of alternative placement options ...
O’Shea, Marie-Claire, Reeves, Nathan E
core   +1 more source

Cellular Physiology and Pathophysiology of EAAT Anion Channels. [PDF]

Front Cell Neurosci, 2021
Kovermann P, Engels M, Müller F, Fahlke C.   +3 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source