Results 101 to 110 of about 2,176,407 (303)
, 2018 Introduction An important topic in cardiac physiology is the relationship between changes in intracardiac pressures and volumes during the cardiac cycle.
Klabunde, Richard +5 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Frontiers in Integrative Physiology
Frontiers in Integrative Physiology is a Specialty Section of Frontiers in Physiology devoted to encompassing the broader aspects of physiology that involve the integration of mechanisms and regulatory functions at all biological levels ranging from the ...
SILVANI, ALESSANDRO
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Semantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology
, 2012 Motivation: The systematic observation of phenotypes has become a crucial tool of functional genomics, and several large international projects are currently underway to identify and characterize the phenotypes that are associated with genotypes in ...
Gkoutos, G. V.; id_orcid +4 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Regulation of translation initiation and modulation of cellular physiology.
, 1993 Translational control of gene expression is an important regulatory mechanism in cellular physiology. In eukaryotes, ribosomes can initiate translation by two different mechanisms: a majority of mRNAs undergo cap-dependent initiation at their extreme 5 ...
Trachsel H, Altmann M
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Clinical physiology: a successful academic and clinical discipline is threatened in Sweden
, 2009 Clinical physiologists in Sweden are physicians (the majority with a PhD degree) with thorough training in system physiology and pathophysiology. They investigate patients in a functional approach and are engaged in basic and applied physiology teaching ...
Arheden, Håkan,, Lund University.
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pH, Carbon Dioxide, Bicarbonate, and Cellular Function
, 1990 The Department of Physiology, University of Pennsylvania School of Medicine, and the Respiratory Physiology Group of that department are organizing an international symposium entitled “pH, Carbon Dioxide, Bicarbonate, and Cellular Function” to be given ...
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source