Results 161 to 170 of about 2,084,390 (260)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Current topics in cellular regulation.

, 1996
Praise for the Series: "Timely ... High standard of Writing ... It is to be highly recommended."--Quarterly Journal of Experimental Physiology This informative publication brings together knowledge of various aspects of cellular regulation.
Stadtman, Earl R., Chock, P. Boon.
core  

TRPV6-Mediated Ca²⁺ Signaling in Pancreatic Ductal Adenocarcinoma: From Cellular Physiology to Therapeutic Opportunities. [PDF]

Cancers (Basel)
Yosef B, Venglovecz V.
europepmc   +1 more source

The Emerging and Diverse Roles of Bis(monoacylglycero) Phosphate Lipids in Cellular Physiology and Disease. [PDF]

Int J Mol Sci, 2020
Showalter MR, Berg AL, Nagourney A, Heil H, Carraway KL, Fiehn O.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Lon protease reprograms cellular physiology of <i>Streptomyces coelicolor</i> resulting in enhance antibiotic production. [PDF]

Front Microbiol
Bayraktar A, Kara S, Demir Z, Okay S, Tunca S.   +4 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The differentiation of myeloid progenitors is effected by cascading waves of coordinated gene expression that remodel cellular physiology in a characteristic sequence. [PDF]

PLoS Comput Biol
Repele A, Handzlik J, Samarawickrama N, Long T, Nooti S, Potluri V, Loh YL, Manu.   +7 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Fusion Pores as Regulators of Quantal Size and Cellular Physiology. [PDF]

Bioessays
Bhaskar BR, Mazumdar S, Dayanandan S, Das D.   +3 more
europepmc   +1 more source