Gene interaction studies in cellular reprogramming of adult stem cells to embyronic like stem cells [PDF]
, 2012 Nishanthi Gangadaran +1 more
openalex +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
Cyclic Stretch Promotes Cellular Reprogramming Process through Cytoskeletal-Nuclear Mechano-Coupling and Epigenetic Modification. [PDF]
Adv Sci (Weinh), 2023 Park SM +15 more
europepmc +1 more source
Translational reprogramming in cellular stress response [PDF]
, 2013 Botao Liu, Shu‐Bing Qian
openalex +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source
Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration. [PDF]
Cell Rep, 2023 Salinas-Saavedra M +5 more
europepmc +1 more source
A general strategy for cellular reprogramming: The importance of transcription factor cross-repression [PDF]
, 2013 Isaac Crespo, Antonio del Sol
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Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Advanced Science, EarlyView.Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou +8 more
wiley +1 more source
Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation. [PDF]
Curr Opin Genet Dev, 2023 Maslov AY, Vijg J.
europepmc +1 more source