Results 121 to 130 of about 114,739 (248)
Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
, 2010 Jacob H. Hanna +2 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang +8 more
wiley +1 more source
Stem Cell Research, 2019 Joubert syndrome (JS) is an autosomal recessive neurodevelopmental disorder, characterized by congenital cerebellar and brainstem defects, belonging to the group of disorders known as ciliopathies, which are caused by mutations in genes encoding proteins
Filomena Altieri +11 more
doaj
Identifying Molecular Roadblocks for Transcription Factor-Induced Cellular Reprogramming In Vivo by Using C. elegans as a Model Organism. [PDF]
J Dev Biol, 2023 Özcan I, Tursun B.
europepmc +1 more source
Genome-wide MyoD Binding in Skeletal Muscle Cells: A Potential for Broad Cellular Reprogramming
, 2010 Yi Cao +11 more
openalex +1 more source
Erratum to: The Cellular Memory Disc of Reprogrammed Cells [PDF]
, 2013 Seyed Hadi Anjamrooz
openalex +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
Innate immunity and epigenetic plasticity in cellular reprogramming [PDF]
, 2014 John P. Cooke +3 more
openalex +1 more source
The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots
Advanced Science, EarlyView.DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya +6 more
wiley +1 more source
The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming. [PDF]
Cells, 2023 Mendoza G +11 more
europepmc +1 more source