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Debugging cellular reprogramming
Nature Cell Biology, 2007Last year it was reported that a cocktail of four transcription factors — encoded by Oct4, Sox2, Myc and Klf4 — can partly reprogramme mouse somatic cells to an embryonic state, a process that reawakens silenced segments of the genome and restores pluripotency to the somatic cell nucleus.
In-Hyun Park, George Q. Daley
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Effects of Cellular Extract on Epigenetic Reprogramming
Cellular Reprogramming, 2019Functional reprogramming of a differentiated cell toward pluripotent cell may have long-term applications in numerous aspects, especially in regenerative medicine. Evidences accumulating from recent studies suggest that cellular extracts from stem cells or pluripotent cells can induce epigenetic reprogramming and facilitate pluripotency in otherwise ...
Xian-Rong, Xiong +5 more
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Small Molecules in Cellular Reprogramming and Differentiation
2010Recent advances in somatic cell reprogramming and directed differentiation make it possible to generate patient-specific pluripotent cells and further derive functional tissue-specific cells for biomedical research and future therapies. Chemical compounds targeting enzymes or signaling proteins are powerful tools to regulate and reveal complex cellular
Xu, Yuan, Wenlin, Li, Sheng, Ding
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The mystique of cellular reprogramming
Current Opinion in Genetics & Development, 2013Huck Hui, Ng, Patrick P L, Tam
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Cellular Reprogramming as a Therapeutic Target in Cancer
Trends in Cell Biology, 2019Lin Cheng
exaly
COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING
2022HODGKINSON CONRAD +3 more
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