Results 181 to 190 of about 239,802 (263)

The Role of Cellular Senescence in Obstructive Airway Diseases: From Mechanisms to Therapeutic Targets. [PDF]

Int J Mol Sci
Vrouvaki A, Moustaka Christodoulou M, Hillas G, Loukides S, Fouka E.   +4 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Cellular Senescence in the Ascending Aorta and Complexity of Coronary Atherosclerosis. [PDF]

J Aging Res
Abanus H, Vural M, Katkat F, Paşaoğlu E, Olgun A, Mert B.   +5 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Disordered differentiation and cellular senescence in pediatric Hodgkin Reed-Sternberg cells. [PDF]

Blood Adv
Agrusa JE, Abdel Fattah E, Lin H, Velazquez J, Salinas SA, Abhyankar HA, Scull BP, Fleischmann R, Elghetany MT, Marcogliese AN, Curry CV, Punia JN, Ozuah NW, Eckstein OS, El-Mallawany NK, Gulati N, Lubega J, Horton TM, Kamdar KY, McClain KL, Man TK, Allen CE.   +21 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

EYA4 promotes cellular senescence by enhancing P21 transcription through interaction with SIX2. [PDF]

Adv Biotechnol (Singap)
Li X, Mao P, Chen D, Li L, Fang H, Huang J, Liu H.   +6 more
europepmc   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

The Yin and Yang of cellular senescence in ischemia-induced myocardial injury. [PDF]

Trends Cardiovasc Med
Wolff von Gudenberg R, Iske J, Roeschl T, Stawowy P, Kirkland JL, Ruhparwar A, Tullius SG.   +6 more
europepmc   +1 more source