Results 231 to 240 of about 234,206 (306)

PCBP2 Regulates p16^INK4a-Dependent Cellular Senescence in Response to Iron. [PDF]

Aging Cell
Yan S, Lu L, Wu Y, Du Z, Johny E, Dutta P, Li G.   +6 more
europepmc   +1 more source

FGF-2 suppresses cellular senescence of human mesenchymal stem cells by down-regulation of TGF-β2

, 2007
Tomomi Ito, Rumi Sawada, Yoko Fujiwara, Yousuke Seyama, Toshie Tsuchiya   +4 more
openalex   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Multifactorial Imaging Analysis as a Platform for Studying Cellular Senescence Phenotypes. [PDF]

J Imaging
Rimma S, Ilya L, Daniil S.
europepmc   +1 more source

Involvement of Matricellular Proteins in Cellular Senescence: Potential Therapeutic Targets for Age-Related Diseases [PDF]

Motomichi Fujita, Manabu Sasada, Takuya Iyoda, Fumio Fukai   +3 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Cellular senescence defining the disease characteristics of Crohn's disease. [PDF]

Front Immunol
Zhang W, Ma X, Tian W, Teng Y, Ji M.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Reprogramming cellular senescence and aging clocks for advanced cancer immunotherapy. [PDF]

Mol Cancer
Yang H, Liu D, Qiu L, Wang R, Zhang C, Yu D, Zhong Q, Yuki N, Song Z, Zhu T, Ju H, Hong W, Zhu J.   +12 more
europepmc   +1 more source

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl3.pdf

Shreshta Jain (12274885), Divya Vohora (11744306)   +1 more
openalex   +1 more source