Results 231 to 240 of about 1,861,365 (381)

Transcriptional Networks and Cellular Senescence in Human Mammary Fibroblasts [PDF]

, 2004
Kristine Hardy, L. Mansfield, Alan Mackay, Silvia Benvenuti, Said I. Ismail, Parineeta Arora, M O'hare, Parmjit Jat   +7 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Cellular senescence defining the disease characteristics of Crohn's disease. [PDF]

Front Immunol
Zhang W, Ma X, Tian W, Teng Y, Ji M.
europepmc   +1 more source

IGFBP-3, a Marker of Cellular Senescence, Is Overexpressed in Human Papillomavirus-Immortalized Cervical Cells and Enhances IGF-1-Induced Mitogenesis [PDF]

, 2004
Astrid Baege, Gary L. Disbrow, Richard Schlegel   +2 more
openalex   +1 more source

The heterogeneity of cellular senescence: insights at the single-cell level.

Trends in Cell Biology, 2022
Rachel L. Cohn, N. Gasek, G. Kuchel, Ming Xu   +3 more
semanticscholar   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

p300 inhibition delays premature cellular senescence. [PDF]

NPJ Aging
Di Fede E, Taci E, Castiglioni S, Rebellato S, Ancona S, Grazioli P, Parodi C, Colombo EA, Bernardelli C, Lesma E, Krantz ID, Corti S, Priori A, Fazio G, Gervasini C, Massa V, Lettieri A.   +16 more
europepmc   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456

EBioMedicine, 2020
LaTonya J. Hickson, Larissa G.P. Langhi Prata, Shane A. Bobart, Tamara K. Evans, Nino Giorgadze, Shahrukh K. Hashmi, Sandra M. Herrmann, Michael D. Jensen, Qingyi Jia, Kyra L. Jordan, Todd A. Kellogg, Sundeep Khosla, Daniel M. Koerber, Anthony B. Lagnado, Donna K. Lawson, Nathan K. LeBrasseur, Lilach O. Lerman, Kathleen M. McDonald, Travis J. McKenzie, João F. Passos, Robert J. Pignolo, Tamar Pirtskhalava, Ishran M. Saadiq, Kalli K. Schaefer, Stephen C. Textor, Stella G. Victorelli, Tammie L. Volkman, Ailing Xue, Mark A. Wentworth, Erin O. Wissler Gerdes, David B. Allison, Stephanie L. Dickinson, Keisuke Ejima, Elizabeth J. Atkinson, Marc Lenburg, Yi Zhu, Tamara Tchkonia, James L. Kirkland   +37 more
doaj  

Cellular Senescence in Human Chondrocytes in Relation to Osteoarthritis. [PDF]

Cartilage
Qiang Y, Zheng C, Maslov AY, Lu Z, Zhou M, Gao J, Ren P, Pang Y, Vijg J.   +8 more
europepmc   +1 more source