Results 31 to 40 of about 1,220 (170)

Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction

Scientific Reports, 2018
Cellulosomes are highly sophisticated molecular nanomachines that participate in the deconstruction of complex polysaccharides, notably cellulose and hemicellulose.
Pedro Bule, Virgínia M. R. Pires, Victor D. Alves, Ana Luísa Carvalho, José A. M. Prates, Luís M. A. Ferreira, Steven P. Smith, Harry J. Gilbert, Ilit Noach, Edward A. Bayer, Shabir Najmudin, Carlos M. G. A. Fontes   +11 more
doaj   +1 more source

Unique organization and unprecedented diversity of the Bacteroides (Pseudobacteroides) cellulosolvens cellulosome system

Biotechnology for Biofuels, 2017
Background (Pseudo) Bacteroides cellulosolvens is an anaerobic, mesophilic, cellulolytic, cellulosome-producing clostridial bacterium capable of utilizing cellulose and cellobiose as carbon sources. Recently, we sequenced the B.
Olga Zhivin, Bareket Dassa, Sarah Moraïs, Sagar M. Utturkar, Steven D. Brown, Bernard Henrissat, Raphael Lamed, Edward A. Bayer   +7 more
doaj   +1 more source

Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose‐Degrading Anaerobic Bacteria

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
The structure and biosynthetic origin of the enigmatic “yellow affinity substance” (YAS) from the anaerobe thermophile Clostridium thermocellum (now: Acetivibrio thermocellus) were elucidated. YAS is a complex of unusual antibacterial arylpolyene alkaloids (celluxanthenes) that are produced by various cellulolytic anaerobes.
Keishi Ishida, Jana Krabbe, Philippe R. Meisinger, Gulimila Shabuer, Sebastian Schieferdecker, Michael Cyrulies, Cedric Tank, Emma Barnes, Christian Paetz, Christian Hertweck   +9 more
wiley   +2 more sources

Improving the Synthesis Efficiency of Amino Acids by Analyzing the Key Sites of Intracellular Self-Assembly of Artificial Cellulosome

Fermentation
To explore the key sites affecting the intracellular assembly of key components of cellulosomes and obtain DocA mutants independent of Ca2+, Swiss-model, GROMACS, PyMOL, and other molecular dynamics simulation software were used for modeling and static ...
Nan Li, Lu Yang, Xiankun Ren, Peng Du, Piwu Li, Jing Su, Jing Xiao, Junqing Wang, Ruiming Wang   +8 more
doaj   +1 more source

Synergies between cellulosomal and non-cellulosomal bacterial cellulases complexed in designer cellulosomes

International Journal of Biological Macromolecules
The development of cellulases cocktails to efficiently solubilize cellulose for biotechnological applications is a constant demand. Cellulases exhibit diverse mode of action, operating in the free state or in multi-enzyme complexes (cellulosomes), and potentially acting synergistically for a higher efficiency.
David, Hélène, Vita, Nicolas, Pagès, Sandrine, Štravs, Petra, Berlec, Aleš, Fierobe, Henri-Pierre, Perret, Stéphanie   +6 more
openaire   +4 more sources

Cellulosomics of the cellulolytic thermophile Clostridium clariflavum [PDF]

Biotechnology for Biofuels, 2014
Clostridium clariflavum is an anaerobic, thermophilic, Gram-positive bacterium, capable of growth on crystalline cellulose as a single carbon source. The genome of C. clariflavum has been sequenced to completion, and numerous cellulosomal genes were identified, including putative scaffoldin and enzyme subunits.Bioinformatic analysis of the C ...
Artzi, Lior, Dassa, Bareket, Borovok, Ilya, Shamshoum, Melina, Lamed, Raphael, Bayer, Edward A   +5 more
openaire   +2 more sources

Impact of scaffoldin mechanostability on cellulosomal activity

Biomaterials Science, 2020
A low mechanostability cohesin between the two cellulosomal anchoring points lowers saccharification activity (top), in contrast to alternative configurations (bottom).
Albert Galera-Prat, Andrés M. Vera, Sarah Moraïs, Yael Vazana, Edward A. Bayer, Mariano Carrión-Vázquez   +5 more
openaire   +4 more sources

Efficient yeast surface-display of novel complex synthetic cellulosomes

Microbial Cell Factories, 2018
Background The self-assembly of cellulosomes on the surface of yeast is a promising strategy for consolidated bioprocessing to convert cellulose into ethanol in one step.
Hongting Tang, Jiajing Wang, Shenghuan Wang, Yu Shen, Dina Petranovic, Jin Hou, Xiaoming Bao   +6 more
doaj   +1 more source

The Cellulosome Paradigm in An Extreme Alkaline Environment

Microorganisms, 2019
Rapid decomposition of plant biomass in soda lakes is associated with microbial activity of anaerobic cellulose-degrading communities. The alkaliphilic bacterium, Clostridium alkalicellulosi, is the single known isolate from a soda lake that demonstrates cellulolytic activity.
Paripok Phitsuwan, Sarah Moraïs, Bareket Dassa, Bernard Henrissat, Edward A. Bayer   +4 more
openaire   +6 more sources

Organization and distribution of the cellulosome in Clostridium thermocellum [PDF]

Journal of Bacteriology, 1985
The properties of the cellulosome (the cellulose-binding, multicellulase-containing protein complex) in Clostridium thermocellum were examined by comparing the cellulase systems derived from the wild type and an adherence-defective mutant. The growth conditions--specifically, growth either on cellulose (Avicel) or on cellobiose as insoluble or soluble ...
E A, Bayer, E, Setter, R, Lamed
openaire   +2 more sources