Actions of Octocoral and Tobacco Cembranoids on Nicotinic Receptors [PDF]
Toxicon, 2009 Nicotinic acetylcholine receptors (AChRs) are pentameric proteins that form agonist-gated cation channels through the plasma membrane. AChR agonists and antagonists are potential candidates for the treatment of neurodegenerative diseases. Cembranoids are
Eterović, Vesna A. +5 more
core +8 more sources
Bioactive Cembranoids from the Soft Coral Sinularia crassa [PDF]
Marine Drugs, 2011 Eight new cembranoids, crassarines A–H (1–8) were isolated from the Formosan soft coral Sinularia crassa. Compounds 1–3 represent the rare cembranoids with a 1,12-oxa-bridged tetrahydrofuran ring, while 4 and 5 are the firstly discovered 1,11-oxa-bridged
Jyh-Horng Sheu +7 more
doaj +8 more sources
Cembranoids from the Dongsha Atoll Soft Coral Lobophytum crassum [PDF]
Marine Drugs, 2011 Chemical investigation of the Dongsha Atoll soft coral Lobophytum crassum has afforded four new cembranoids, crassumols A–C (1–3) and 13-acetoxysarcophytoxide (4).
Shang-Kwei Wang +2 more
doaj +7 more sources
Anti-Inflammatory Cembranoids from a Formosa Soft Coral Sarcophyton cherbonnieri [PDF]
Marine Drugs, 2020 The present investigation on chemical constituents of the soft coral Sarcophyton cherbonnieri resulted in the isolation of seven new cembranoids, cherbonolides F–L (1–7).
Chia-Chi Peng +4 more
doaj +3 more sources
Bioactive Cembranoids from the Coral Sarcophyton trocheliophorum of Ximao Island. [PDF]
ACS Omega, 2022 Eight new cembranoids (sarcophytembranoids A–H, 1–8) and 10 known terpenoids (9–18) were obtained from the soft coral Sarcophyton trocheliophorum of Ximao Island. Notably, 11, 15, and 16 were obtained from a natural source for the first time.
Zeng ZR +6 more
europepmc +2 more sources
An Improved Synthesis of 7, 8-Epoxy-1,3,11-cembratriene-15R(α), 16-diol, a Cembranoid of Marine Origin with a Potent Cancer Chemopreventive Activity [PDF]
Marine Drugs, 2004 An effective method for the synthesis of 7,8-epoxy-1,3,11-cembratriene-15R(α), 16-diol and its in vitro Epstein-Barr Virus Early Antigen (EBV-EA) Activation Chemopreventive Assay are reported.
Sherief I. Khalifa +3 more
doaj +2 more sources
Six Undescribed Capnosane-Type Macrocyclic Diterpenoids from South China Sea Soft Coral Sarcophyton crassocaule: Structural Determination and Biological Evaluation [PDF]
Marine Drugs, 2023 Six undescribed capnosane-type macrocyclic diterpenes sarcocrassolins A–F (1–6) and one related known analog pavidolide D (7) were isolated from Sarcophyton crassocaule, a soft coral collected off the Nansha Islands, in the South China Sea.
Hanyang Peng +7 more
doaj +2 more sources
Computationally Assisted Structural Elucidation of Cembranoids from the Soft Coral Sarcophyton tortuosum. [PDF]
Mar Drugs, 2022 A persistent study on soft coral Sarcophyton tortuosum resulted in the characterization of two new cembranolides, tortuolides A and B (1 and 2), and a new related diterpene, epi-sarcophytonolide Q.
Chao CH +6 more
europepmc +2 more sources
Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp. [PDF]
Marine Drugs, 2011 Four new cembranoids, lobophylins A–D (1–4), and one novel secocembrane, lobophylin E (5) were isolated from a soft coral Lobophytum sp. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods.
Jyh-Horng Sheu +3 more
doaj +4 more sources
Sarcoconvolutums F and G: Polyoxygenated Cembrane-Type Diterpenoids from Sarcophyton convolutum, a Red Sea Soft Coral [PDF]
Molecules, 2022 Natural products and chemical analogues are widely used in drug discovery, notably in cancer and infectious disease pharmacotherapy. Sarcophyton convolutum (Alcyoniidae) a Red Sea–derived soft coral has been shown to be a rich source of macrocyclic ...
Tarik A. Mohamed +9 more
doaj +2 more sources