Results 61 to 70 of about 2,095 (251)

Oxygenated Cembranoids from the Soft Coral Sinularia flexibilis [PDF]

International Journal of Molecular Sciences, 2013
Chemical examination of the Taiwanese soft coral Sinularia flexibilis led to the isolation of five cembrane-based diterpenoids 1–5, including two new metabolites, 11-acetylsinuflexolide (1) and 11-acetyldihydrosinuflexolide (2). The structures of the new metabolites were determined based on extensive spectroscopic analysis, particularly mass ...
Ching-Chyuan Su, Bing-Sang Wong, Yu-Jen Wu, Jui-Hsin Su, Chuen Chin   +4 more
openaire   +2 more sources

Cytotoxic and Antibacterial Cembranoids from a South China Sea Soft Coral, Lobophytum sp.

Marine Drugs, 2013
Chemical examination of a South China Sea soft coral Lobophytum sp. led to the isolation of three new α-methylene-γ-lactone-containing cembranoids, (1R*,3R*, 4R*,14R*,7E,11E)-3,4-epoxycembra-7,11,15(17)-trien-16,14-olide (1), (1R*,7S*,14S*,3E, 11E)-7 ...
Kexin Huang, Zheng Xiang, Jianyong Dong, Xinxiang Lei, Minshan Ma, Wei Jiang, Jian Yin, Min Zhao, Pengcheng Yan   +8 more
doaj   +1 more source

New Antiproliferative Cembrane Diterpenes from the Red Sea Sarcophyton Species

Marine Drugs, 2019
The combination of liquid chromatography coupled to high resolution mass spectrometry (LC-HRESMS)-based dereplication and antiproliferative activity-guided fractionation was applied on the Red Sea-derived soft coral Sarcophyton sp.
Hossam M. Hassan, Mostafa E. Rateb, Marwa H. Hassan, Ahmed M. Sayed, Samah Shabana, Mai Raslan, Elham Amin, Fathy A. Behery, Osama M. Ahmed, Abdullatif Bin Muhsinah, Tobias A. M. Gulder, Usama Ramadan Abdelmohsen   +11 more
doaj   +1 more source

Suppression of Migration and Invasion by 4-Carbomethoxyl-10-Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells. [PDF]

Adv Pharmacol Pharm Sci
The primary reason for cancer‐related fatalities is metastasis. The compound 4‐carbomethoxyl‐10‐epigyrosanoldie E, derived from the Sinularia sandensis soft coral species grown in cultures, exhibits properties that counteract inflammation. Moreover, it has been observed to trigger both apoptosis and autophagy within cancerous cells.
Fang RY, Liu YW, Goan YG, Lin JJ, Su JH, Wu WT, Wu YJ.   +6 more
europepmc   +2 more sources

Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action. [PDF]

, 2013
The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this review, following the format used in the 1998–2008 reviews of this series.
A. D. Rodriguez, A. M. S. Mayer, N. Fusetani, TAGLIALATELA SCAFATI, ORAZIO   +3 more
core   +2 more sources

New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi

Marine Drugs, 2014
Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1–3 as well as the previously reported marine cembranoid diterpene sarcophine (4).
Ahmed Elkhateeb, Ahmed A. El-Beih, Amira M. Gamal-Eldeen, Montaser A. Alhammady, Shinji Ohta, Paul W. Paré, Mohamed-Elamir F. Hegazy   +6 more
doaj   +1 more source

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine [PDF]

, 2006
The soft coral Sarcophyton glaucum is a rich resource of several bioactive cembranoids. Sarcophytol A (1) and sarcophine (2) are cembranoid diterpenes reported from this soft coral and extensively investigated for their cancer chemopreventive properties.
El Sayed, Khalid A., Ferniz, Melissa, Marchetti, Dario, Reiland, Jane, Sawant, Swapnali S., Youssef, Diaa T.A.   +5 more
core   +2 more sources

Cembranoids from the Vietnamese soft coral Sarcophyton ehrenbergi

Natural Product Research, 2021
Using various chromatographic separations, two new cembranoids, ehrenbergols F and G (1 and 2), along with three known analogs ehrenbergol D (3), (+)-isosarcophine (4) and sinulariol Z2 (5) were isolated from the soft coral Sarcophyton ehrenbergi.
Ngoc Ninh Thi, Hanh Tran Thi Hong, Q. Tran Hong, Cuong Nguyen Xuan, N. Nguyen Hoai, Do Thi Thao, P. Cuong, Thung Do Cong, Kiem Phan Van, Chau Van Minh   +9 more
semanticscholar   +1 more source

Biscembranoids and Cembranoids from the Soft Coral Sarcophyton elegans [PDF]

Marine Drugs, 2017
Two novel biscembranoids, sarelengans A and B (1 and 2), five new cembranoids, sarelengans C–G (3–7), along with two known cembranoids (8 and 9) were isolated from the South China Sea soft coral Sarcophyton elegans. Their structures were determined by spectroscopic and chemical methods, and those of 1, 4, 5, and 6 were confirmed by single crystal X-ray
Lan-Lan Lou, Abrar Ahmed, Yun-Shao Xu, Gui-Hua Tang, Wei Li, Sheng Yin, Man-Xi Ge, Yunyun Chen, Yi-Hong Zou, Jun-Sheng Zhang   +9 more
openaire   +3 more sources

Modifications of Prenyl Side Chains in Natural Product Biosynthesis

Angewandte Chemie, Volume 136, Issue 52, December 20, 2024.
This review summarizes the unique modifications of prenyl side chains involved in natural product biosynthesis, including epoxidation, dehydrogenation, oxidation of methyl groups to carboxyl groups, C−C bond cleavage and oxidative cyclization. Abstract In recent years, there has been a growing interest in understanding the enzymatic machinery ...
Huibin Wang, Yi Yang, Ikuro Abe
wiley   +2 more sources