Ferroptosis Inhibits Cementoblast Mineralization Via Cgas-Sting/Gpx4 Axis [PDF]
International Dental JournalAim or purpose: To investigate the role of the cGAS-STING/GPX4 axis in ferroptosis and its impact on cementoblast mineralization under compressive force, and its involvement in orthodontically induced inflammatory external root resorption (OIIERR ...
Tian Wei, Dongyang Li, Chunmiao Jiang
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Triethylene-glycol-dimethacrylate induces caspase-mediated apoptotic cell death in cementoblasts by the regulation of JNK and p38 pathways-an in vitro study [PDF]
Journal of Dental SciencesBackground/Purpose: Triethylene-glycol-dimethacrylate (TEGDMA) is one of the monomers used in composite resin matrix. Residual TEGDMA can be eluted from bulk fill composite resins and the amounts also increased with time. Composite resin used as root-end
Wei-Ju Lai +4 more
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Galectin-3 Plays an Important Role in BMP7-Induced Cementoblastic Differentiation of Human Periodontal Ligament Cells by Interacting with Extracellular Components [PDF]
Stem Cells International, 2023 Human periodontal ligament stem cells (hPDLSCs) contain multipotent postnatal stem cells that differentiate into PDL progenitors, osteoblasts, and cementoblasts.
Min-Jeong Choi +2 more
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Bone Morphogenetic Protein 7 Promotes the Differentiation of Periodontal Ligament Fibroblasts into F-Spondin-Expressing Cementoblast-like Cells During Root Canal Treatment—An In Vivo Rat Pulpectomy Model and In Vitro Human Fibroblast Study [PDF]
Dentistry JournalBackground/Objectives: The optimal healing process following root canal treatment involves biological apical sealing through new cementum formation.
Hiroki Iwasawa +5 more
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Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes [PDF]
Stem Cells International, 2022 Root resorption is a common dental challenge that can lead to tooth loosening or even tooth loss. Among the cells involved in root resorption, cementoblasts are responsible for laying down the cementum, while macrophages with different phenotypes have ...
Yi Zhao +6 more
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Restoration of Cementoblast Mineralization by Glutamine Under Inflammatory Conditions [PDF]
International Dental Journal: Introduction and Aims: Cementoblasts are critical for cementum formation and periodontal regeneration during inflammatory diseases such as periodontitis and apical periodontitis (AP). Bacterial infection leads to metabolic changes in cementoblasts and
Mengjie Yin +10 more
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Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study [PDF]
Biological Procedures Online, 2023 Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi +4 more
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Effect of local injection of injectable platelet-rich fibrin on eruption rate of teeth (Rabbit animal model) [PDF]
Journal of Orthodontic Science, 2023 OBJECTIVE: This study aimed to evaluate the effect of the local injection of injectable platelet-rich fibrin (i-PRF) on the eruption rate of the teeth and evaluation of the effect of i-PRF on the number of odontoblast, cementoblast, osteoblast, osteocyte,
Enas Talb Al-Jwary +1 more
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Cementum regeneration strategies: Insights from development and periodontal microenvironment [PDF]
Frontiers in Cell and Developmental BiologyCementum, a mineralized tissue covering the root surface of the tooth, maintains tooth stability through providing support for the attachment of periodontal ligament fibres, and protects the pulp from external damage via acting as a barrier against ...
Huiyi Wang +11 more
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Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy [PDF]
Bioactive MaterialsCementum, a thin layer of mineralized tissue covering tooth root surface, is recognized as the golden standard in periodontal regeneration. However, current efforts mainly focus on alveolar bone regeneration rather than cementum regeneration, and rarely ...
Xin Huang +5 more
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