Results 41 to 50 of about 1,301 (143)

Kdm6b/Pdk1 Glycolytic Pathway-Driven Zeb2 Lactylation Promotes Cementogenesis

International Dental Journal
Aim or purpose: This study investigates the role of KDM6B-mediated glycolytic reprogramming in cementum regeneration, addressing the unclear mechanisms linking epigenetic-metabolic crosstalk to cementoblast mineralization.
Wang Xiaoxuan, Wang Huiyi, Yang Zhengkun, Cao Zhengguo   +3 more
doaj   +1 more source

The four mechanisms of dental resorption initiation

Dental Press Journal of Orthodontics, 2013
The aim of this study is to present a classification with a clinical application for root resorption, so that diagnosis will be more objective and immediately linked to the source of the problem, leading the clinician to automatically develop the likely ...
Alberto Consolaro
doaj   +1 more source

LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling

International Journal of Oral Science, 2023
Orthodontically induced tooth root resorption (OIRR) is a serious complication during orthodontic treatment. Stimulating cementum repair is the fundamental approach for the treatment of OIRR.
Tiancheng Li, Han Wang, Yukun Jiang, Shuo Chen, Danyuan Huang, Zuping Wu, Xing Yin, Chenchen Zhou, Yuyu Li, Shujuan Zou   +9 more
doaj   +1 more source

Extrusion Techniques—Clinical Applications of Modern Tooth Preservation Concepts and Their Comparison

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To present and compare several extrusion techniques in case of insufficient tooth structure to create a sufficient ferrule and consider the biological width. Clinical Considerations Extrusion methods based on orthodontic or surgical techniques are commonly applied, well‐described, and predictable extrusion methods. Elastics with the
Elisabeth Völler, Michael Stimmelmayr, Jan‐Frederik Güth, Stefan Neumeyer, Daniel Edelhoff, Pauline Gutmann, Tobias Graf   +6 more
wiley   +1 more source

Osteogenic potential of periodontal ligament stem cells are unaffected after exposure to lipopolysaccharides

Brazilian Oral Research
Periodontitis develops as a result of a continuous interaction between host cells and subgingival pathogenic bacteria. The periodontium has a limited capacity for regeneration, probably due to changes in periodontal ligament stem cells (PDLSCs) phenotype.
Mayra Laino ALBIERO, Bruna Rabelo AMORIM, Márcio Zaffalon CASATI, Enilson Antonio SALLUM, Francisco Humberto NOCITI JUNIOR, Karina Gonzales SILVÉRIO   +5 more
doaj   +1 more source

Wnt/β-catenin pathway regulates cementogenic differentiation of adipose tissue-deprived stem cells in dental follicle cell-conditioned medium. [PDF]

PLoS ONE, 2014
The formation and attachment of new cementum is crucial for periodontium regeneration. Tissue engineering is currently explored to achieve complete, reliable and reproducible regeneration of the periodontium. The capacity of multipotency and self-renewal
Na Liu, Bin Gu, Ning Liu, Xin Nie, Bo Zhang, Xia Zhou, Manjing Deng   +6 more
doaj   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Periodontal considerations during orthodontic intrusion and extrusion in healthy and reduced periodontium

Periodontology 2000, EarlyView.
Abstract In patients with advanced periodontal disease, pathological tooth migration may occur, which may require subsequent orthodontic treatment for both aesthetic and functional purposes. When planning orthodontic treatment mechanics, intrusive or extrusive forces are frequently indicated.
Gregory S. Antonarakis, Alkisti Zekeridou, Stavros Kiliaridis, Catherine Giannopoulou   +3 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source