Results 171 to 180 of about 113,938,265 (213)

Centromere A Protein (CENP-A) [PDF]

, 2008
openaire   +1 more source

A genomic and epigenomic view of human centromeres. [PDF]

Nat Rev Genet
Jaggi KE, Hoyt SJ, O'Neill RJ, Sullivan BA.   +3 more
europepmc   +1 more source

Chromosome condensation mechanically primes the nucleus for mitosis. [PDF]

EMBO J
Nunes V, Moura M, Silva SF, Vareiro D, Audugé N, Borghi N, Ferreira JG.   +6 more
europepmc   +1 more source

Mitotic Machinery Dysregulation in Lung Cancer: Biological Roles, Therapeutic Targeting, and Combination Strategies. [PDF]

Pharmaceutics
Pinto B, Silva JPN, Silva PMA, Sarmento B, Carvalho-Tavares J, Bousbaa H.   +5 more
europepmc   +1 more source

Genome instability triggers intercellular DNA transfer between human cells. [PDF]

Cell
Maurais EG, Mazzagatti A, Lin YF, Narozna M, Hu Q, Dahiya R, Santiago-Ferrer D, Herlihy CP, Krebs M, Pateraki N, Parcharidou E, Papathanasiou S, Beliveau BJ, Gorbsky GJ, Cortés-Ciriano I, Ly P.   +15 more
europepmc   +1 more source

Models for the architecture of the human inner kinetochore CCAN complex on centromeric α-satellite CENP-A nucleosome arrays

Barford D, Yu C, Muir K, Yang J, Zhang Z, McLaughlin S.   +5 more
europepmc   +1 more source

Cryo‐EM structure of the CENP‐A nucleosome in complex with phosphorylated CENP‐C

EMBO Journal, 2021
The CENP-A nucleosome is a key structure for kinetochore assembly. Once the CENP-A nucleosome is established in the centromere, additional proteins recognize the CENP-A nucleosome to form a kinetochore. CENP-C and CENP-N are CENP-A binding proteins. We previously demonstrated that vertebrate CENP-C binding to the CENP-A nucleosome is regulated by CDK1 ...
Hitoshi Kurumizaka, Masatoshi Hara, Tatsuo Fukagawa   +2 more
exaly   +4 more sources

CENP ‐C unwraps the human CENP ‐A nucleosome through the H2A C‐terminal tail [PDF]

EMBO Reports, 2019
Centromeres are defined epigenetically by nucleosomes containing the histone H3 variant CENP-A, upon which the constitutive centromere-associated network of proteins (CCAN) is built. CENP-C is considered to be a central organizer of the CCAN.
Nikolina Sekulic, Mario Halic, Nikolina Sekulic   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

The ABCs of CENPs

Chromosoma, 2011
Equal distribution of DNA in mitosis requires the assembly of a large proteinaceous ensemble onto the centromeric DNA, called the kinetochore. With few exceptions, kinetochore specification is independent of the DNA sequence and is determined epigenetically by deposition at the centromeric chromatin of special nucleosomes containing an H3-related ...
Marinela, Perpelescu, Tatsuo, Fukagawa
openaire   +2 more sources

CENP-A and the CENP nomenclature: response to Talbert and Henikoff

Trends in Genetics, 2013
Earlier this year, we, along with 55 additional investigators worldwide who with us are collectively responsible for a large majority of the literature on the components and function of centromeres and their attached kinetochores, published our recommendation [1] that the original name ‘centromere protein A’ (‘CENP-A’) continue in general use to refer ...
William C, Earnshaw, Don W, Cleveland
openaire   +2 more sources