Results 11 to 20 of about 7,373 (166)

The Immune Cell Atlas of "Longevity Molecular Tag": Identification of Principal Immune Cell Subsets and Their Underlying Molecular Regulatory Mechanisms. [PDF]

Aging Cell
This study aims to develop an immune cell atlas of the “Longevity Molecular Tags” by employing the Scissor algorithm to identify key immune cell subsets associated with longevity phenotypes. Subsequently, the underlying immune molecular mechanisms contributing to the longevity‐associated immune cell subsets were investigated through differential gene ...
Zhang Z, Su H, Fu S, Ji F, Liang L, Song W, Hu C, Wei L, Long E, Lin Y, Ni X.   +10 more
europepmc   +2 more sources

Stronger bilateral functional connectivity of the frontoparietal control network in near-centenarians and centenarians without dementia

NeuroImage, 2020
Centenarians without dementia can be considered as a model of successful ageing and resistance against age-related cognitive decline. Is there something special about their brain functional connectivity that helps them preserve cognitive function into ...
Jiyang Jiang, Tao Liu, John D. Crawford, Nicole A. Kochan, Henry Brodaty, Perminder S. Sachdev, Wei Wen   +6 more
doaj   +1 more source

Trophic ulcers of the lower extremities in centenarians: are there any features?

Клинический разбор в общей медицине, 2023
Aim. To compare various clinical and laboratory parameters in centenarians and old patients with trophic ulcers of the lower extremities. Materials and methods.
Leonid I. Bubman, Svetlana V. Topolyanskaya, Viktor V. Karpov, Stanislav O. Khan, Mariya А. Korshunova, Karine A. Lytkina, Georgii G. Melkonya, Svetlana A. Rachina, Leonid I. Dvoretsky   +8 more
doaj   +1 more source

Global Research on Centenarians: A Historical and Comprehensive Bibliometric Analysis from 1887 to 2023 [PDF]

Annals of Geriatric Medicine and Research
Background Centenarians are considered the most successful human biological aging model. However, the characteristics and patterns of research among centenarians have not been described or analyzed.
Ivan David Lozada-Martinez, Maria Carolina Diazgranados-Garcia, Sandra Castelblanco-Toro, Juan-Manuel Anaya   +3 more
doaj   +1 more source

A Comparative Study on the Health Status and Behavioral Lifestyle of Centenarians and Non-centenarians in Zhejiang Province, China—A Cross-Sectional Study

Frontiers in Public Health, 2019
Background: The growth rate of centenarians was unusually rapid in recent decades, ushering in an era of longevity. This study aims to explore the difference between centenarians and non-centenarians using quantitative research, and to scientifically ...
Chao Rong, Chao Rong, Shu-Hua Shen, Lu-Wei Xiao, Qi Huang, Han-Ti Lu, Hong-Xian Wang, Zheng-Xiang Li, Xiao-Ming Wang   +8 more
doaj   +1 more source

Associations of immunological factors with metabolic syndrome and its characteristic elements in Chinese centenarians

Journal of Translational Medicine, 2018
Background Metabolic syndrome (MetS) has an increased prevalence (approximately 20–25% of the adult population) all over the world. Immunological function is significantly associated with the development of MetS, and MetS is beginning to be considered as
Shihui Fu, Yao Yao, Faqin Lv, Fu Zhang, Yali Zhao, Fuxin Luan   +5 more
doaj   +1 more source

Heart Rate Variability and Exceptional Longevity

Frontiers in Physiology, 2020
Centenarians are the paradigm of human extreme longevity and healthy aging, because they have postponed, if not avoided, mayor age-related diseases. The purpose of this study was to investigate potential differences in resting heart rate variability (HRV)
Adrián Hernández-Vicente, Adrián Hernández-Vicente, David Hernando, David Hernando, Alejandro Santos-Lozano, Alejandro Santos-Lozano, Gabriel Rodríguez-Romo, Gabriel Rodríguez-Romo, Germán Vicente-Rodríguez, Germán Vicente-Rodríguez, Germán Vicente-Rodríguez, Germán Vicente-Rodríguez, Esther Pueyo, Esther Pueyo, Raquel Bailón, Raquel Bailón, Nuria Garatachea, Nuria Garatachea, Nuria Garatachea, Nuria Garatachea   +19 more
doaj   +1 more source

The relationship between depressive mood and subjective health in centenarians and near-centenarians: a cross-sectional study from Korean centenarian cohort

The Aging Male, 2023
Background With the rapid increase in population longevity, more clinical attention is being paid to the overall health of long-lived people, especially centenarians.
Min Jhon, Min-Ho Shin, Kyung Chul Yoon, Jeong-Sun Kim, Jeonghwa Lee, Kwangsung Park, Sang Chul Park   +6 more
doaj   +1 more source

Descriptive and predictive analysis identify centenarians' characteristics from the Basque population

Frontiers in Public Health, 2023
BackgroundCentenarians exhibit extreme longevity and have been postulated, by some researchers, as a model for healthy aging. The identification of the characteristics of centenarians might be useful to understand the process of human aging.MethodsIn ...
Sara Cruces-Salguero, Igor Larrañaga, Igor Larrañaga, Javier Mar, Javier Mar, Javier Mar, Ander Matheu, Ander Matheu, Ander Matheu   +8 more
doaj   +1 more source

A comparison of perceived uselessness between centenarians and non-centenarians in China

BMC Geriatrics, 2018
Background Self-perceived uselessness is associated with poorer health in older adults. However, it is unclear whether there is a difference in self-perceived uselessness between centenarians and non-centenarians, and if so, which factors contributed to ...
Yuan Zhao, Hong Fu, Aimei Guo, Li Qiu, Karen S. L. Cheung, Bei Wu, Daniela Jopp, Danan Gu   +7 more
doaj   +1 more source