Results 261 to 270 of about 751,175 (304)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Coagulation process for the removal of color and turbidity from wet coffee processing industry wastewater using bio-coagulant: Optimization through central composite design. [PDF]

Heliyon
Getahun M, Befekadu A, Alemayehu E.
europepmc   +1 more source

OPTIMIZATION OF THE SELECTIVE CATALYTIC REDUCTION OF NO IN DIESEL EXHAUST OVER CU-ZN/ZSM-5 CATALYST USING CENTRAL COMPOSITE DESIGN

, 2010
Ahmad Zuhairi Abdullah, Hamidah Abdullah, Subhash Bhatia, Babak Salamatinia, Noraini Razali   +4 more
openalex   +2 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Syrupy herbal formulation of green bean pod extract of Phaseolus vulgaris L.: Formulation optimization by central composite design, and evaluation for anti-urolithiatic activity. [PDF]

Heliyon
Noorulla KM, Doyo Dalecha D, Jemal Haji M, S R, Arumugam M, Zafar A, Gadisa Gobena W, Mekit S, Haji Negawo H, Hussein M, Fekadu Demessie H, Yasir M.   +11 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Central composite design and mechanism of antibiotic ciprofloxacin photodegradation under visible light by green hydrothermal synthesized cobalt-doped zinc oxide nanoparticles. [PDF]

Sci Rep
Hassaan MA, Meky AI, Fetouh HA, Ismail AM, El Nemr A.   +4 more
europepmc   +1 more source

Relationship between sintering pressure and leach rate of polycrystalline diamond compacts (PDCs) using central composite design (CCD) modelling

Andrew Ndlovu, Lesley Cornish, H.S.L. Sithebe   +2 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source