Results 271 to 280 of about 215,784 (311)

Model Simulation Study of Central Composite Design and Uniform Design

SAE Technical Paper Series, 2007
<div class="htmlview paragraph">The relationship between the response (output) and the input factors on a system or process is always needed. This relationship can be used to optimize the response. The Central Composite Design (CCD) is the most commonly used in response surface study. The Uniform Design (UD) can have a small number of experiments
Ming-Wei Lu, Marlon D. Forrest, Cheng Julius Wang   +2 more
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The Application of Central Composite Design in Flash Spinning

Advanced Materials Research, 2011
In this paper, ultrahigh molecular weight polyethylene (UHMWPE) superfine fiber was fabricated by flash-spinning method using UHMWPE as the fiber-forming polymer, 1, 2-dichloroethane as the main solvent. Use central composite design principle, the four factors which mainly influenced the properties of the fiber: spinning temperature, spinning pressure,
Lei Xia, Peng Xi, Bo Wen Cheng
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Design and Optimization of Domperidone Fast Dissolving Tablet Using Central Composite Design

Current Drug Delivery, 2015
The main aim present work was to optimize fast dissolving tablet (FDT) formulation using response surface approach. The variables studied were sodium bicarbonate (X1), citric acid (X2), and superdisintegrant, Ac-Di-Sol (X3). The main aspect of present work was to develop FDT of Domperidone which possesses fast disintegration and high mechanical ...
Bhatt, Shailendra, Mandge, Shailendra, Jaimini, Manish, Tanwar Yuveraj, Singh, Trivedi, Priti   +4 more
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Central composite design in the chiral analysis of amphetamines by capillary electrophoresis

ELECTROPHORESIS, 1997
AbstractWe have studied a central composite design for the chiral separation of amphetamines using capillary electrophoresis. Five variables, i.e., buffer concentration, pH, chiral selector concentration, temperature, and applied voltage, were investigated.
Varesio, Emmanuel, Gauvrit, Jean-Yves, Longeray, Rémi, Lantéri, Pierre, Veuthey, Jean-Luc   +4 more
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Formulation of Fenofibrate Liquisolid Tablets Using Central Composite Design

Current Drug Delivery, 2014
Liquisolid technique has been widely used to enhance the dissolution of poorly water soluble drugs. The present investigation is on formulation of liquisolid tablets of fenofibrate, a lipid lowering agent. Liquisolid formulation was prepared by applying central composite design (CCD) to optimize various formulation parameters.
Tejas, Patel, L D, Patel, B N, Suhagia, Tejal, Soni, Tushar, Patel   +4 more
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Optimized synthesis of polyglutaraldehyde nanoparticles using central composite design

Journal of Pharmaceutical Sciences, 1988
A central composite design was applied to the optimization of the synthesis of polyglutaraldehyde nanoparticles (PGNP). The effects of monomer concentration, surfactant concentration, pH, oxygen level, and stirring rate on the particle size, polydispersity, surface carboxyl group concentration, and yield of PGNP were investigated.
A D, McLeod, F C, Lam, P K, Gupta, C T, Hung   +3 more
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Two‐strata rotatability in split‐plot central composite designs

Applied Stochastic Models in Business and Industry, 2009
AbstractA rotatable design (Ann. Math. Stat.1957;28:195–241) forkfactors is one such that the prediction variance is purely a function of distance from the design center. Of special interest in this paper is the rotatable central composite design (CCD), which most software packages use as the typical default choice for a second‐order design.
Wang, Li, Vining, G. Geoffrey, Kowalski, Scott M.   +2 more
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Application of Central Composite Design to Simulation Experiment

2005
This paper proposes a strategy using the common random numbers and antithetic variates in simulation experiments that utilize the central composite design for estimating the second-order model. This strategy assigns the common random numbers to the cubic points and a center, and the antithetic variates to the axial points and one center. An appropriate
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Central Composite Experimental Designs for Multiple Responses With Different Models

Technometrics, 2019
Central composite designs (CCDs) are widely accepted and used experimental designs for fitting second-order polynomial models in response surface methods.
Wilmina M. Marget, Max D. Morris
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C432. Efficiency comparisons of central composite designs

Journal of Statistical Computation and Simulation, 1995
(1995). C432. Efficiency comparisons of central composite designs. Journal of Statistical Computation and Simulation: Vol. 52, No. 2, pp. 177-183.
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