Thermosensitive Hydrogels Loaded with Resveratrol Nanoemulsion: Formulation Optimization by Central Composite Design and Evaluation in MCF-7 Human Breast Cancer Cell Lines [PDF]
Sabna Kotta +5 more
openalex +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Innovative design of composite structures: Further studies in the use of a curvilinear fiber format to improve structural efficiency [PDF]
Further studies to determine the potential for using a curvilinear fiber format in the design of composite laminates are reported. The curvilinear format is in contrast to the current practice of having the fibers aligned parallel to each other and in a ...
Charette, Robert F., Hyer, Michael W.
core +1 more source
Linear and non-linear dynamic analyses of sandwich panels with face sheet-tocore debonding [PDF]
А survey of recent developments in the dynamic analysis of sandwich panels with face sheet-to-core debonding is presented. The finite element method within the ABAQUSTM code is utilized.
Burlayenko, V. N., Sadowski, Tomasz
core
Adaptive development and maintenance of user-centric software systems [PDF]
A software system cannot be developed without considering the various facets of its environment. Stakeholders – including the users that play a central role – have their needs, expectations, and perceptions of a system.
Alspaugh +24 more
core +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Uncertain Loading and Quantifying Maximum Energy Concentration within Composite Structures [PDF]
We introduce a systematic method for identifying the worst case load among all boundary loads of fixed energy. Here the worst case load is defined to be the one that delivers the largest fraction of input energy to a prescribed subdomain of interest. The
Lipton, Robert +2 more
core +3 more sources
The objective of the present study was to obtain the optimum proportion of the carbon source and prebiotics for Bifidobacterium bifidum BB01 by the central composite design (CCD).
Shu Guowei +4 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Design Efficiency and Optimal Values of Replicated Central Composite Designs with Full Factorial Portions [PDF]
Iwundu M.P., Oko E.T.
openalex +1 more source

