Results 1 to 10 of about 3,481 (110)

To split or to lump? Classifying the central disorders of hypersomnolence. [PDF]

Sleep, 2020
Abstract The classification of the central disorders of hypersomnolence has undergone multiple iterations in an attempt to capture biologically meaningful disease entities in the absence of known pathophysiology. Accumulating data suggests that further refinements may be necessary.
Fronczek R, Arnulf I, Baumann CR, Maski K, Pizza F, Trotti LM.   +5 more
europepmc   +9 more sources

Cerebrospinal fluid monoamine levels in central disorders of hypersomnolence. [PDF]

Sleep, 2021
Abstract Study Objectives Whether the cause of daytime sleepiness in narcolepsy type 1 (NT1) is a direct consequence of the loss of orexin (ORX) neurons or whether low orexin reduces the efficacy of the monoaminergic systems to promote wakefulness is unclear.
Barateau L, Jaussent I, Roeser J, Ciardiello C, Kilduff TS, Dauvilliers Y.   +5 more
europepmc   +6 more sources

Differences in Sleep Spindle Characteristics Between Children With Narcolepsy and Those With Other Causes of Subjective Sleepiness. [PDF]

J Sleep Res
ABSTRACT Central disorders of hypersomnolence are characterised by excessive daytime sleepiness. There has been growing interest in analysing sleep micro‐architecture, to further understand how sleep is affected by these conditions. We investigated if sleep spindle activity differed between children with narcolepsy, idiopathic hypersomnolence (IH) and ...
Shetty M, Kishore NK, Plunkett G, Nisbet LC, Davey MJ, Nixon GM, Walter LM, Horne RSC.   +7 more
europepmc   +2 more sources

Cerebrospinal fluid orexin testing in Australians with narcolepsy type 1. [PDF]

Intern Med J
Abstract A clinical diagnosis of narcolepsy type 1 can be challenging, particularly in relation to cataplexy. Despite its specificity, cerebrospinal fluid (CSF) orexin testing is under‐utilised in Australasia. We describe the use of CSF orexin testing in 15 clinically indicated patients from two sleep centres, highlighting its utility in the ...
Fernando M, Cotta G, Kung S, Garden G, Tai JE, Matar E, Yee B, Ellender C, Sivam S.   +8 more
europepmc   +2 more sources

International Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (iSPHYNCS): the impact of psychiatric comorbidities on daily life in central disorders of hypersomnolence-a vicious circle. [PDF]

J Sleep Res
Aktan Suzgun M, Wenz ES, van der Meer J, Fregolente LG, Warncke JD, Miano S, Acker J, Strub M, Olliges E, Khatami R, Schmidt MH, iSPHYNCS Investigators, Bassetti CLA, von Manitius S.   +13 more
europepmc   +2 more sources

A case study of acceptance and commitment therapy for central disorders of hypersomnolence: opportunities to improve patient-centered and comprehensive treatment approaches. [PDF]

J Clin Sleep Med
Roth AJ, Foldvary-Schaefer N.
europepmc   +2 more sources

Predictors for Successful Non‐Invasive Ventilation in Patients With Neuralgic Amyotrophy and Phrenic Nerve Involvement

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Phrenic nerve involvement in neuralgic amyotrophy (NA) may cause diaphragm paresis and respiratory impairment, for which chronic non‐invasive ventilation (NIV) may be beneficial. Data on treatment success and predictors are lacking.
A. B. Hendrikx, R. T. Sprooten, B. A. Vosse, S. C. Steijns, S. M. van Kuijk, J. G. Hoeijmakers, F. M. Franssen   +6 more
wiley   +1 more source

Metrology of two wearable sleep trackers against polysomnography in patients with sleep complaints

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep trackers are used widely by patients with sleep complaints, however their metrological validation is often poor and relies on healthy subjects. We assessed the metrological validity of two commercially available sleep trackers (Withings Activité/Fitbit Alta HR) through a prospective observational monocentric study, in adult patients ...
Justine Frija, Jimmy Mullaert, Laure Abensur Vuillaume, Mathieu Grajoszex, Ruben Wanono, Hélène Benzaquen, Fedja Kerzabi, Pierre Alexis Geoffroy, Boris Matrot, Théo Trioux, Thomas Penzel, Marie‐Pia d'Ortho   +11 more
wiley   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Risk of Hypertension and Mortality Among People With Narcolepsy or Idiopathic Hypersomnia: A Retrospective Cohort Analysis of the Danish National Patient Registry

Journal of Sleep Research, EarlyView.
This retrospective cohort study using data from the Danish National Patient Registry shows that individuals with narcolepsy or idiopathic hypersomnia have greater prevalence and risk of incident hypertension compared with matched controls, highlighting the elevated cardiovascular risk associated with these conditions.
Poul Jørgen Jennum, Michael Ibsen, Sam Mettam, Sarah C. Markt, Douglas S. Fuller, Jessica K. Alexander, Rikke Ibsen, Jakob Kjellberg, Caroleen Drachenberg   +8 more
wiley   +1 more source