The growing toolkit for evaluation of central disorders of hypersomnolence. [PDF]
Plante DT.
europepmc +3 more sources
Central Disorders of Hypersomnolence. [PDF]
This article discusses the central disorders of hypersomnolence, a group of disorders resulting in pathologic daytime sleepiness, particularly narcolepsy type 1 and narcolepsy type 2, idiopathic hypersomnia, and Kleine-Levin syndrome. Disease features, diagnostic testing, epidemiology, pathophysiology, and treatment are reviewed.Increasing evidence ...
Trotti LM.
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Present and Future of Central Disorders of Hypersomnolence. [PDF]
ABSTRACT Central disorders of hypersomnolence (CDH) are rare neurological conditions lumped by excessive daytime sleepiness (EDS) as primary complaint mostly arising at young age, including narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), idiopathic hypersomnia (IH), and Kleine‐Levin syndrome (KLS).
Biscarini F +4 more
europepmc +3 more sources
Cannabis Use in Central Disorders of Hypersomnolence in the Netherlands. [PDF]
<p>Introduction: The endocannabinoid system plays a role in sleep-wake regulation. In clinical practice, people with central disorders of hypersomnolence (CDH) frequently report use of cannabis. Methods: We compared lifetime and current use of cannabis of people with CDH to the Dutch general population.
Vringer M +6 more
europepmc +3 more sources
Data-Driven Phenotyping of Central Disorders of Hypersomnolence With Unsupervised Clustering. [PDF]
Recent studies fueled doubts as to whether all currently defined central disorders of hypersomnolence are stable entities, especially narcolepsy type 2 and idiopathic hypersomnia. New reliable biomarkers are needed, and the question arises of whether current diagnostic criteria of hypersomnolence disorders should be reassessed.
Gool JK +28 more
europepmc +11 more sources
Central Disorders of Hypersomnolence: Focus on the Narcolepsies and Idiopathic Hypersomnia. [PDF]
The central disorders of hypersomnolence are characterized by severe daytime sleepiness, which is present despite normal quality and timing of nocturnal sleep. Recent reclassification distinguishes three main subtypes: narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia (IH), which are the focus of this review.
Khan Z, Trotti LM.
europepmc +4 more sources
Brain fog in central disorders of hypersomnolence: a review. [PDF]
Brain fog is an undefined term describing a cluster of symptoms related to fatigue and impaired memory, attention, and concentration. Brain fog or brain fog-like symptoms have been reported in central disorders of hypersomnolence and in a range of seemingly unrelated disorders, including coronavirus disease 2019, major depressive disorder, multiple ...
Rosenberg R +3 more
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Compromised Dynamic Cerebral Autoregulation in Patients With Central Disorders of Hypersomnolence. [PDF]
Objective: We aimed to investigate the dynamic cerebral autoregulation (dCA) in patients with central disorders of hypersomnolence during wakefulness.Methods: Thirty-six patients with central disorders of hypersomnolence were divided into three groups according to polysomnography and multiple sleep latency test results: the idiopathic hypersomnia group
Deng F +7 more
europepmc +5 more sources
Data-Driven Phenotyping of Central Disorders of Hypersomnolence With Unsupervised Clustering. [PDF]
europepmc +4 more sources
Management of Central Disorders of Hypersomnolence in Pregnancy and Lactation. [PDF]
Over 37% of pregnant women report excessive daytime sleepiness or hypersomnia during the first trimester, and commonly throughout the remaining trimesters of pregnancy and the postpartum period. The clinical presentation and symptoms of central disorders of hypersomnolence (CDH) such as narcolepsy, idiopathic hypersomnia, or excessive daytime ...
Abideen ZU +5 more
europepmc +2 more sources

