Results 41 to 50 of about 2,021,144 (357)

Central nervous system involvement by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)

Journal of Medical Virology, 2020
Neurologic sequelae can be devastating complications of respiratory viral infections. We report the presence of virus in neural and capillary endothelial cells in frontal lobe tissue obtained at postmortem examination from a patient infected with severe ...
A. Paniz‐Mondolfi, C. Bryce, Z. Grimes, R. Gordon, J. Reidy, J. Lednicky, E. Sordillo, M. Fowkes   +7 more
semanticscholar   +1 more source

Microglia Function in the Central Nervous System During Health and Neurodegeneration.

Annual Review of Immunology, 2017
Microglia are resident cells of the brain that regulate brain development, maintenance of neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct from other tissue macrophages owing to their unique homeostatic ...
M. Colonna, O. Butovsky
semanticscholar   +1 more source

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Abeta1-42 is a self-associating peptide whose neurotoxic derivatives are thought to play a role in Alzheimer's pathogenesis. Neurotoxicity of amyloid beta protein (Abeta) has been attributed to its fibrillar forms, but experiments presented here ...
M. Lambert, A. Barlow, B. Chromy, C. Edwards, R. Freed, M. Liosatos, Todd E. Morgan, I. Rozovsky, B. Trommer, K. Viola, P. Wals, Zhang Chi, C. Finch, G. Krafft, W. Klein   +14 more
semanticscholar   +1 more source

Brainstem syndrome at onset is related to an early MS diagnosis in Peru: A national referral center cohort

Heliyon, 2021
Background: MS is unpredictable regarding clinical symptoms; however, certain symptoms represent the preferred localization of white matter lesions such as brainstem, spinal cord; or optic nerve.
César Caparó-Zamalloa, Sheila Castro-Suarez, Jaqueline Cortez-Escalante, Wilfor Aguirre-Quispe, Erik Guevara-Silva, Victor Osorio-Marcatinco, María Meza-Vega   +6 more
doaj  

The Central Nervous System

, 2010
[Figure: see text]
De Lorenzi Davide, MANDARA, Maria Teresa
openaire   +3 more sources

Establishment and validation of a prediction model for self-absorption probability of chronic subdural hematoma

Frontiers in Neurology, 2022
BackgroundChronic subdural hematoma (CSDH) is common in elderly people with a clear or occult traumatic brain injury history. Surgery is a traditional method to remove the hematomas, but it carries a significant risk of recurrence and poor outcomes.
Ye Tian, Ye Tian, Ye Tian, Ye Tian, Dong Wang, Dong Wang, Dong Wang, Dong Wang, Xinjie Zhang, Xinjie Zhang, Xinjie Zhang, Xinjie Zhang, Huijie Wei, Huijie Wei, Huijie Wei, Huijie Wei, Yingsheng Wei, Yingsheng Wei, Yingsheng Wei, Yingsheng Wei, Shuo An, Shuo An, Shuo An, Shuo An, Chuang Gao, Chuang Gao, Chuang Gao, Chuang Gao, Jinhao Huang, Jinhao Huang, Jinhao Huang, Jinhao Huang, Jian Sun, Rongcai Jiang, Rongcai Jiang, Rongcai Jiang, Rongcai Jiang, Jianning Zhang, Jianning Zhang, Jianning Zhang, Jianning Zhang   +40 more
doaj   +1 more source

PLK4 initiates crosstalk between cell cycle, cell proliferation and macrophages infiltration in gliomas

Frontiers in Oncology, 2022
Tumor immune microenvironment plays an important role in tumorigenesis and metastasis. Polo-like kinases 4 (PLK4) is a crucial regulatory factor in the process of cell cycle, and its abnormal regulation often leads to a variety of diseases including ...
Xiaoyang Zhang, Zesheng Li, Cheng Wei, Lin Luo, Shenghui Li, Junhu Zhou, Hao Liang, Ying Li, Lei Han   +8 more
doaj   +1 more source

TSPO deficiency promotes the progression of malignant peripheral sheath tumors by regulating the G2/M phase of the cell cycle via CDK1

Scientific Reports
Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive Schwann cell-derived sarcomas that are sporadic or associated with Neurofibromatosis 1 (NF1) gene mutations. Traditional therapies are usually ineffective for treating MPNSTs, so new
Xingnan Zhang, Chenhao Hu, Shengqiao Sun, Chao Guo, Yakun Bu, Zicong Wang, Zewei Liu, Xiaoli Zhang, Dezhi Li, Song Liu   +9 more
doaj   +1 more source

Atorvastatin combined with dexamethasone in chronic subdural haematoma (ATOCH II): study protocol for a randomized controlled trial

Trials, 2021
Background Chronic subdural haematoma (CSDH) is a common condition in the elderly that often requires neurosurgical management. For small CSDH, evidence has emerged that statins may reduce haematoma volume and improve outcomes, presumably by reducing ...
Rong Cai Jiang, Dong Wang, Shi Guang Zhao, Ren Zhi Wang, De Zhi Kang, Xin Gen Zhu, Zong Mao Zhao, Jun Ji Wei, Ying Huang, Yan Qu, Xiao Chuan Sun, Hong Ming Ji, Xiao Chun Jiang, Jin Fang Liu, Xi De Zhu, Jian Jun Wang, Ye Tian, Chuang Gao, Hui Jie Wei, Shu Zhang, Wei Quan, Shu Yuan Yue, Ping Lei, Xian Li, Li Li Song, Craig S. Anderson, Jian Ning Zhang   +26 more
doaj   +1 more source

The evolution of nervous system centralization [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2008
It is yet unknown when and in what form the central nervous system in Bilateria first came into place and how it further evolved in the different bilaterian phyla. To find out, a series of recent molecular studies have compared neurodevelopment in slow-evolving deuterostome and protostome invertebrates, such as the enteropneust ...
Detlev Arendt, Kristin Tessmar-Raible, Gáspár Jékely, Alexandru S. Denes   +3 more
openaire   +4 more sources