Results 91 to 100 of about 1,580,164 (331)
Current pharmaceutical design, 2020 An important goal of biomedical research is to translate basic research findings into practical clinical implementation. Despite the advances in the technology used in drug discovery, the development of drugs for central nervous system diseases remains ...
Y. Morofuji, Shinsuke Nakagawa
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Histopathological Frequency of Central Nervous System Diseases
Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental CollegeObjective: To determine the frequency of central nervous system diseases, both neoplastic and nonneoplastic, by methodically examining data from various age and gender groups.
Prih Bashir +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System
Micromachines, 2020 Neurodegenerative diseases are among the most severe problems in aging societies. Various conventional experimental models, including 2D and animal models, have been used to investigate the pathogenesis of (and therapeutic mechanisms for ...
Mihyeon Bae +3 more
doaj +1 more source
Immune cognition, social justice and asthma: structured stress and the developing immune system [PDF]
, 2001 We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is conjoined with central nervous system cognition, and with the cognitive function of the ...
Fullilove, Mindy +2 more
core
Brain and Behavior, 2020 Leonurus japonicus Houtt., a traditional Chinese herbal medicine, is often used as a gynecological medicine with the effect of promoting blood circulation, regulating menstruation, clearing heat, and detoxificating.
Lu Huang +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Final results of project on feline spongiform encephalopathy [PDF]
, 2006 Feline spongiform encephalopathy (FSE) is a transmissible spongiform encephalopathy associated with the accumulation of an abnormal isoform of the prion protein (PrPsc) in the Central Nervous System. This research allowed to identify other neurological
Cantile, Carlo +9 more
core
The Isotropic Fractionator as a Tool for Quantitative Analysis in Central Nervous System Diseases [PDF]
, 2016 One major aim in quantitative and translational neuroscience is to achieve a precise and fast neuronal counting method to work on high throughput scale to obtain reliable results.Here we tested the Isotropic Fractionator (IF) method for evaluating ...
Alessandro Vercelli +7 more
core +2 more sources