Results 101 to 110 of about 1,580,164 (331)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Exercise for endurance and strength:Always separate? [PDF]
, 2019 Physical training can be classified into three main types: endurance, resistance, and patterned movements. The first two of them have a significant impact on muscle phenotype and metabolism while patterned movement exercises concern changes in a motor ...
Clark, Cain C.T. +3 more
core +1 more source
Viral diseases of the central nervous system [PDF]
Current Opinion in Virology, 2015 Virus-induced diseases of the central nervous system (CNS) represent a significant burden to human health worldwide. The complexity of these diseases is influenced by the sheer number of different neurotropic viruses, the diverse routes of CNS entry, viral tropism, and the immune system.
Phillip A, Swanson, Dorian B, McGavern
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Clinical application of sialic acid (II) Sialic acid contents in cerebro-spinal fluid of patients suffering from the disease of the central nervous system [PDF]
, 1959 It is well known that human serum contains some sialic acid and its contents increase markedly in the blood serum of the patients bearing malignant tumors.
Kanbayashi, Tsuneo +3 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Community Lynching and the US Asthma Epidemic [PDF]
, 2003 We explore the implications of IR Cohen's work on immune cognition for understanding rising rates of asthma morbidity and mortality in the US. Immune cognition is inherently linked with central nervous system cognition, and with the cognitive function ...
Fullilove, Mindy +2 more
core
Contactin-2/TAG-1, active on the front line for three decades [PDF]
, 2017 Contactin-2/transiently expressed axonal surface glycoprotein-1 (TAG-1) is a cell adhesion molecule belonging to the immunoglobulin superfamily (IgSF).
Masuda Tomoyuki, 増田 知之
core +2 more sources
Progress in neurobiology, 2019 Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes are involved in various central nervous system (CNS) diseases ...
Xiaohuan Xia +5 more
semanticscholar +1 more source
Bioprinting Neural Systems to Model Central Nervous System Diseases
Advanced Functional Materials, 2020 To date, pharmaceutical progresses in central nervous system (CNS) diseases are clearly hampered by the lack of suitable disease models. Indeed, animal models do not faithfully represent human neurodegenerative processes and human in vitro 2D cell ...
Boning Qiu +7 more
semanticscholar +1 more source