Results 101 to 110 of about 24,516,016 (295)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Primary lymphoproliferative diseases of the central nervous system

Терапевтический архив, 2009
Primary CNS lymphomas have worse prognosis than other extranodal lymphomas: remissions are rare, recurrences are frequent. Literature is analysed on diagnosis, prognostic factors, perspectives and problems of treatment of primary CNS lymphomas.
ndrey Vladimirovich Gubkin, Evgeniy Evgen'evich Zvonkov, Aleksandra Mikhaylovna Kremenetskaya, Sergey Kirillovich Kravchenko, Andrey Ivanovich Vorob'ev, A V Gubkin, E E Zvonkov, A M Kremenetskaya, S K Kravchenko, A I Vorobyev   +9 more
doaj  

Central nervous system parasites

When parasitic infections of the Central Nervous System (CNS) are examined, we encounter quite a lot of parasites. Among protozoans, especially free-living amoebae (such as Naegleria, Acanthamoeba, Balamuthia, and Sappinia) have attracted attention in ...
Aydinli, A.
core  

The development of the central nervous system and human neural stem cells

The development of the nervous system is a long process that begins during early stages of embryonic growth. Morphologically, primordial structures of the nervous system begin to form during the neurulation process. This then continues with the formation
Ascenzi, Brandon, Dr. Ávila-Macaya, Ariel, Dra. Vidal-Vera, Pía   +2 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Microglial ferroptosis mediated neuroinflammation in central nervous system diseases

Brain Research Bulletin
Microglial ferroptosis has become an important pathological mechanism in studies of central nervous system (CNS) diseases. Rather than being viewed only as an endpoint of cell death, ferroptosis in microglia is increasingly recognized as a process that ...
Shu-xian Ren, Feng-jing Jia, Jing Zhu, Jian-ren Liu, Hai-dong Guo, Guo-hong Cui   +5 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

KAT5: the epigenetic regulator of central nervous system diseases

Frontiers in Molecular Neuroscience
Abnormal epigenetic modifications are involved in central nervous system (CNS) diseases. Histones play a crucial role in chromatin structure and function, whose post-translational modifications significantly impact gene expression and chromatin dynamics.
Xiaoming Xin, Lingjuan Wu, Meichen Liu, Tian Liu, Zihan Yuan, Liang Zhang, Tongqing Duan, Lei Zhang, Xianmin Zhu   +8 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Graphdiyne biomaterials: from characterization to properties and applications

Journal of Nanobiotechnology
Graphdiyne (GDY), the sole synthetic carbon allotrope with sp-hybridized carbon atoms, has been extensively researched that benefit from its pore structure, fully conjugated surfaces, wide band gaps, and more reactive C≡C bonds.
Ling-Xiao Zhao, Yong-Gang Fan, Xue Zhang, Chan Li, Xue-Yan Cheng, Feng Guo, Zhan-You Wang   +6 more
doaj   +1 more source