Results 161 to 170 of about 24,516,016 (295)

Brain targeting and trafficking of extracellular vesicles in central nervous system diseases: a therapeutic roadmap. [PDF]

open access: yesNanomedicine (Lond)
Baker B   +11 more
europepmc   +1 more source

The primate nervous system.

open access: yes, 1999
This volume is the third and final part of the planned coverage of the neurochemical circuitry of the primate central nervous system. The five chapters included in this volume complement and integrate magnificently with the two prior volumes. Included in
Bloom, Floyd E.edt   +1 more
core  

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin   +11 more
wiley   +1 more source

Neutrophil Extracellular Traps in Central Nervous System Diseases. [PDF]

open access: yesCurr Neuropharmacol
Zhu J, Zhu H, Hou W, Liu JY.
europepmc   +1 more source

Diagnostic value of NMO-IgG in demyelinating diseases of central nervous system

open access: yes, 2016
The aquaporin 4 (AQP4) plays an important role in the maintenance of transmembrane water transfer, blood-brain barrier (BBB) integrity and homeostasis of central nervous system, and its highly specific autoantibody NMO-IgG has been used as a specific ...
You-dong WEI, Xiao-min XU
core  

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui   +10 more
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu   +10 more
wiley   +1 more source

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