Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms [PDF]
Frontiers in Oncology, 2023 Central nervous system (CNS) neoplasms are difficult to treat due to their sensitive location. Over the past two decades, the availability of patient tumor materials facilitated large scale genomic and epigenomic profiling studies, which have resulted in
Yao Lulu Xing +2 more
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The Continuing Value of Ultrastructural Observation in Central Nervous System Neoplasms in Children [PDF]
Journal of Pathology and Translational Medicine, 2015 Central nervous system (CNS) neoplasms are the second most common childhood malignancy after leukemia and the most common solid organ neoplasm in children. Diagnostic dilemmas with small specimens from CNS neoplasms are often the result of multifactorial
Na Rae Kim, Sung-Hye Park
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Intraoperative Frozen Cytology of Central Nervous System Neoplasms: An Ancillary Tool for Frozen Diagnosis [PDF]
Journal of Pathology and Translational Medicine, 2019 Background Pathologic diagnosis of central nervous system (CNS) neoplasms is made by comparing light microscopic, immunohistochemical, and molecular cytogenetic findings with clinicoradiologic observations.
Myunghee Kang +18 more
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Primary central nervous system neoplasms in African hedgehogs. [PDF]
J Vet Diagn Invest, 2018 In this retrospective study, we describe the clinicopathologic and immunohistochemical findings in a series of primary central nervous system (CNS) neoplasms in African hedgehogs ( Atelerix albiventris). Twelve CNS neoplasms were found among 762 African hedgehog submissions (1.6%) to a private diagnostic laboratory in an 18-y period. The median age of
Muñoz-Gutiérrez JF +2 more
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Immunohistochemical Study of Ki-67 Labelling Index in Neoplasms of Central Nervous System [PDF]
National Journal of Laboratory Medicine, 2022 Introduction: The central nervous system tumours show a varied histopathological spectrum. The cell proliferation index may provide an objective method for assessing tumour biology. The Ki-67 is considered to be the most reliable proliferative marker
Anuradha G Patil +3 more
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Mast cells in central nervous system neoplasms: an immunohistochemical study
Revista Mexicana de Neurociencia, 2023 Objective: To investigate the relationship between mast cells (MCs) and different central nervous system (CNS) tumors. Methods: It was a comparative immunohistochemical study to investigate the presence, number, and location of MCs in pilocytic ...
Aldair Ochoa-Rojas +6 more
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Radiotherapy in Current Neuro-Oncology: There Is Still Much to Reveal
Life, 2021 Radiation therapy (RT) has a pivotal role in the treatment of Central Nervous System (CNS) neoplasms and is routinely employed for both benign and malignant lesions [...]
Gianluca Ferini +1 more
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Not all roses are sweet—Pediatric ependymoma
Journal of the American College of Emergency Physicians Open, 2023 Ependymomas are rare malignant neoplasms that originate from radial glial cells within the central nervous system. Within pediatric central nervous tumors, ependymomas constitute the third most common entity with the majority occurring within the ...
George V. Koshy +2 more
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Modulation of the Complement System by Neoplastic Disease of the Central Nervous System
Frontiers in Immunology, 2021 The complement system is a highly conserved component of innate immunity that is involved in recognizing and responding to pathogens. The system serves as a bridge between innate and adaptive immunity, and modulation of the complement system can affect ...
Steven K. Yarmoska +4 more
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Smear technique for intraoperative diagnosis of central nervous system neoplasms
Journal of Pathology of Nepal, 2014 Background: Smear cytology has become increasily popular as an alternative to frozen section for the rapid diagnosis of most of central nervous system lesions.
S Shrestha, BK Thapa, B Bhattarai
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