Results 61 to 70 of about 25,848,997 (286)

Therapeutic electrical stimulation of the central nervous system

open access: yesComptes Rendus. Biologies, 2005
The electrical effects on the nervous system have been known for long. The excitatory effect has been used for diagnostic purposes or even for therapeutic applications, like in pain using low-frequency stimulation of the spinal cord or of the thalamus.
Benabid, Alim-Louis   +9 more
openaire   +5 more sources

Retrospective Review of Trend in Modafinil Overexposures Reported to American Poison Information Centers [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Background:Modafinil, a non-amphetamine central nervous system stimulant, is a wakefulness-promoting agent indicated for use in shift work sleep disorder, narcolepsy, and obstructive sleep apnea. The trend in modafinil overexposure over a ten-year period
Kristin Bohnenberger, Edward Krenzelok
doaj  

Prevalence of and factors associated with the use of methylphenidate for cognitive enhancement among university students

open access: yesEinstein (São Paulo), 2019
Objective To estimate the prevalence of and factors associated with the use of methylphenidate for cognitive enhancement among undergraduate students.
Raissa Carolina Fonseca Cândido   +3 more
doaj   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Consumption of Central Nervous System Stimulants among Medical and Nursing Students at a Chilean University

open access: yesSMAD: Revista Eletrônica Saúde Mental Álcool e Drogas, 2013
El estudio objetivó determinar la prevalencia de consumo de psicoestimulantes, en estudiantes de enfermería y medicina de una universidad chilena, las características personales y motivaciones para lo consumo de estas sustancias.
Carmen Gloria-Garcés   +1 more
doaj  

Blood pressure, heart rate and CNS stimulant medication use in children with and without ADHD: analysis of NHANES data

open access: yesFrontiers in Pediatrics, 2014
It is estimated that 2-3% of children in the US have hypertension (HTN) and 8% of children ages 4-17 carry the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD).
Susan M Hailpern   +6 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Mechanisms of Magnetic Stimulation of Central Nervous System Neurons

open access: yesPLoS Computational Biology, 2011
Transcranial magnetic stimulation (TMS) is a stimulation method in which a magnetic coil generates a magnetic field in an area of interest in the brain. This magnetic field induces an electric field that modulates neuronal activity. The spatial distribution of the induced electric field is determined by the geometry and location of the coil relative to
Tamar Pashut   +6 more
openaire   +4 more sources

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