Results 61 to 70 of about 44,555 (311)
The soluble form of Toll-like receptor 2 is elevated in serum of multiple sclerosis patients: a novel potential disease biomarker [PDF]
, 2018 Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of the central nervous system. It was previously shown that Toll-like receptor (TLR)-2 signalling plays a key role in the murine experimental autoimmune encephalomyelitis ...
Andersen +46 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Retrospective Review of Trend in Modafinil Overexposures Reported to American Poison Information Centers [PDF]
Asia Pacific Journal of Medical Toxicology, 2014 Background:Modafinil, a non-amphetamine central nervous system stimulant, is a wakefulness-promoting agent indicated for use in shift work sleep disorder, narcolepsy, and obstructive sleep apnea. The trend in modafinil overexposure over a ten-year period
Kristin Bohnenberger, Edward Krenzelok
doaj
Frontiers in Pediatrics, 2014 It is estimated that 2-3% of children in the US have hypertension (HTN) and 8% of children ages 4-17 carry the diagnosis of Attention Deficit Hyperactivity Disorder (ADHD).
Susan M Hailpern +6 more
doaj +1 more source
Metoprolol treatment of dual cocaine and bupropion cardiovascular and central nervous system toxicity [PDF]
Clinical and Experimental Emergency Medicine, 2019 Cardiovascular and central nervous system (CNS) toxicity, including tachydysrhythmia, agitation, and seizures, may arise from cocaine or bupropion use.
John R. Richards +3 more
doaj +1 more source
Poisoning with illicit substances: toxicology for the anaesthetist [PDF]
, 2013 The consumption of illicit substances represents a considerable threat to the health and wellbeing of particular sectors of our communities. Hospitalisation is sometimes required for the treatment of the direct toxic effects of the drugs as well as for ...
Irwin, MG, Wong, GTC
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Role of radiology in central nervous system stimulation [PDF]
The British Journal of Radiology, 2015 Central nervous system (CNS) stimulation is becoming increasingly prevalent. Deep brain stimulation (DBS) has been proven to be an invaluable treatment for movement disorders and is also useful in many other neurological conditions refractory to medical treatment, such as chronic pain and epilepsy.
D P, Minks +4 more
openaire +2 more sources
Influence of Quadrato Motor Training on Salivary proNGF and proBDNF [PDF]
, 2019 Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF).
Ben-Soussan, Tal D. +4 more
core +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source