Primary hypersomnia (PH) is a disorder of presumed central nervous system etiology that is associated with a normal or prolonged major sleep episode and excessive sleepiness consisting of prolonged (one or two hour) episodes of non-rapid eye movement ...
John Dinesh +2 more
doaj
Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch +9 more
wiley +1 more source
Central Nervous System Stimulants Limit Caffeine Transport at the Blood-Cerebrospinal Fluid Barrier. [PDF]
Ikeda-Murakami K +4 more
europepmc +1 more source
The effect of stimulants on irritability in autism comorbid with ADHD: a systematic review
Ahmad Ghanizadeh,1,2 Mohammed Molla,2 Garth Jon Olango21Research Center for Psychiatry and Behavioral Sciences, Department of Psychiatry, Shiraz University of Medical Sciences, Shiraz, Iran; 2Department of Psychiatry, UCLA-Kern Psychiatry Residency ...
Ghanizadeh A, Molla M, Olango GJ
doaj
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
New Application of 123I-Iodoamphetamine SPECT for the Diagnosis of Primary Central Nervous System Lymphoma [PDF]
123I-iodoamphetamine (IMP) single photon emission computed tomography (SPECT) is used to evaluate the cerebral blood flow (CBF) in patients with either cerebrovascular or neurodegenerative diseases [3 6].
SHIBATA Yasushi, Yasushi Shibata
core +1 more source
Objective The diagnosis of fibromyalgia (FM) is challenging due to the absence of definitive biomarkers, numerous overlapping comorbidities, and its reliance on patient‐reported symptoms. Discrepancies between diagnostic criteria and clinical practice imply the possibility of diagnostic biases, complicating timely and accurate identification.
Sung‐A Kim +2 more
wiley +1 more source
Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis
Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir +9 more
wiley +1 more source
Use of stimulant drugs among high school adolescents in a Metropolitan Region: a school-based study [PDF]
Objective: to identify the prevalence of stimulant drugs among adolescents in high school and the associated factors. Method: cross-sectional study with 4,614 adolescents between 14 and 19 years old. Descriptive, bivariate (chi-square test and Fisher’
Franciéle Marabotti Costa Leite +6 more
doaj +6 more sources
The pharmacology and toxicology of the stimulant khat
Khat chewing has a long history in the culture and society of the Horn of Africa and Yemen. Extracts of leaves from khat have similar actions to that of amphetamines and contain the major psychostimulant cathinone, but also the mainly peripherally acting
Hadeel A. Alsufyani
doaj +1 more source

