Results 81 to 90 of about 271,718 (292)

Dynamics-based centrality for general directed networks

open access: yes, 2010
Determining the relative importance of nodes in directed networks is important in, for example, ranking websites, publications, and sports teams, and for understanding signal flows in systems biology.
A. Berman   +12 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Inflow and outflow centrality: novel centrality metrics inspired by graph convolution

open access: yesApplied Network Science
Centrality metrics quantify a node’s importance within a network based on a node’s connectivity, path position, proximity to other nodes, or influence from neighbors.
Aram Papazian, Volkhard Helms
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Peer Effects and Social Networks in Education [PDF]

open access: yes
This paper studies whether structural properties of friendship networks affect individual outcomes in education. We first develop a model that shows that, at the Nash equilibrium, the outcome of each individual embedded in a network is proportional to ...
Calvó-Armengol, Antoni   +2 more
core   +3 more sources

On the Distributions of Subgraph Centralities in Complex Networks

open access: yesDiscrete Dynamics in Nature and Society, 2013
Subgraph centrality measure characterizes the participation of each node in all subgraphs in a network. Smaller subgraphs are given more weight than large ones, which makes this measure appropriate for characterizing network motifs.
Faxu Li   +3 more
doaj   +1 more source

The myth of patient centrality [PDF]

open access: yes, 2007
Purpose: The purpose of this paper is to critically examine the extent of patient centrality within integrated chronic back pain management services and compare policy rhetoric with practice reality.
Haigh, C, Howarth, ML
core  

Distance entropy cartography characterises centrality in complex networks

open access: yes, 2018
We introduce distance entropy as a measure of homogeneity in the distribution of path lengths between a given node and its neighbours in a complex network.
De Domenico, Manlio, Stella, Massimo
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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