Results 81 to 90 of about 495,738 (354)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Physical Modelling of Geotechnical Structures in Ports and Offshore

open access: yesPolish Maritime Research, 2017
The physical modelling of subsoil behaviour and soil-structure interaction is essential for the proper design of offshore structures and port infrastructure.
Bałachowski Lech
doaj   +1 more source

About the separation of finely divided particles during centrifugation in liquid media

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2018
This work is devoted to the study of centrifugation processes, which are one of the most complex processes of technology. The use of the action of the centrifugal force field for the separation of heterogeneous liquid systems in a rotor system ...
A. B. Kydyrbekuly   +3 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

SEPARAÇÃO SÓLIDO-LÍQUIDO: CENTRÍFUGAS E PAPÉIS DE FILTRO

open access: yesQuímica Nova, 2015
This work describes the fundamentals and evolution of two current solid-liquid separation methods found in the chemical laboratory: the filter paper and the centrifuge.
Alexander Rangel Bastos   +1 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Wireless temperature calibration for medical centrifuge

open access: yesSensors International
Based on the complexity and metrological requirements of temperature calibration within the rotor of a medical low-temperature centrifuge, a wireless temperature calibration device for medical centrifuges has been designed and developed.
Tianyu Zhu   +4 more
doaj   +1 more source

Avocado oil extraction processes: method for cold-pressed high-quality edible oil production versus traditional production

open access: yesJournal of Agricultural Engineering, 2015
Nowadays the avocado fruit (Persea americana Mill.) is widely regarded as an important fruit for its nutritional values, as it is rich in vital human nutrients.
Giacomo Costagli, Matteo Betti
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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