Results 71 to 80 of about 175 (153)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Osteohistological sampling on different bones of theropod dinosaur documents discrepant age record, growth, and metabolism. This could result unprecise paleobiological inferences if samplings are based on single bones. However, multi‐bone sampling can attenuate these discrepancies, helping to infer growth dynamics and physiology of these extinct ...
Geovane Alves de Souza +3 more
wiley +1 more source
Further Insights Into the Mechanisms of Lymph Node Metastasis
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson +5 more
wiley +1 more source
Using dual‐energy X‐ray absorptiometry clustering of 185 treatment‐naïve type 2 diabetes patients, we identified four body‐composition phenotypes. Central‐obesity and high‐fat–high‐muscle clusters carried the highest fatty liver disease and hyperuricemia risk, whereas the low‐muscle cluster carried the highest osteoporosis risk.
Xintong Zhang, Rui Zhang, Tao Jiang
wiley +1 more source
ABSTRACT Background Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized. Methods A 79‐year‐old female with recurrent left oral tongue SCC (PD‐L122C3 Combined Positive Score 90) who ...
Andreja Radevic +9 more
wiley +1 more source
Contrast‐Enhanced Ultrasonography of Orbital and Intraocular Pathologies in 24 Dogs and 6 Cats
ABSTRACT Objective Contrast‐enhanced ultrasonography (CEUS) is a noninvasive and relatively safe imaging technique to assess ocular perfusion, showing high sensitivity and specificity for tumor characterization in human oncology, while reports on its application in canine and feline diseased eyes are limited.
Janneke I. Ortner +3 more
wiley +1 more source
Redundancy, Diversity, and Modularity in Network Resilience: Applications for International Trade and Implications for Public Policy. [PDF]
Kharrazi A +4 more
europepmc +1 more source
An ecological framework for the analysis of prebiotic chemical reaction networks. [PDF]
Peng Z, Plum AM, Gagrani P, Baum DA.
europepmc +1 more source
Sparks of life: Enabling multi‐scale investigations of pro‐arrhythmic calcium‐handling abnormalities
The Journal of Physiology, EarlyView.
Melania Buonocunto, Jordi Heijman
wiley +1 more source
Culturo-behavioral Hypercycles and the Metacontingency: Incorporating Self-Organizing Dynamics into an Expanded Model of Cultural Change. [PDF]
Krispin J.
europepmc +1 more source

