Time of gene expression in relation to centromere distance during the cell cycle of Saccharomyces cereviseae. [PDF]
, 1968 P. Tauro, H. O. Halvorson, R. Epstein
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Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
International Journal of Cancer, EarlyView.Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert +3 more
wiley +1 more source
Constitutive centromere-associated network controls centromere drift in vertebrate cells
Journal of Cell Biology, 2017 Centromeres are specified by sequence-independent epigenetic mechanisms, and the centromere position may drift at each cell cycle, but once this position is specified, it may not be frequently moved.
T. Hori +8 more
semanticscholar +1 more source
SOMATIC INSTABILITY OF TELOCENTRIC CHROMOSOMES IN WHEAT AND THE NATURE OF THE CENTROMERE [PDF]
, 1966 Lotti M Steinitz-Sears
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T2T genome, pan‐genome analysis, and heat stress response genes in Rhododendron species
iMeta, EarlyView.This study reports the first high‐quality telomere‐to‐telomere (T2T) Rhododendron liliiflorum genome with 11 chromosomes that are gap free. The 24 telomeres and all 13 centromeres detected in this genome, which reached the highest quality gold level.
Xiaojing Wang +8 more
wiley +1 more source
The kinetochore prevents centromere-proximal crossover recombination during meiosis
eLife, 2015 During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination is non-random across the genome, and centromere-proximal crossovers are associated with an increased ...
Nadine Vincenten +9 more
semanticscholar +1 more source
Centromere assembly requires selective recognition of centromeric chromatin by centromere protein N
The FASEB Journal, 2008 The kinetochore is a unique chromosomal locus that binds to the mitotic spindle so that chromosomes can segregate in mitosis. Kinetochore assembly requires the specialized chromatin of the centromere that is distinguished by the replacement of histone H3 with the histone H3‐variant centromere protein A (CENP‐A). CENP‐A is thought to epigenetically mark
Christopher W. Carroll +1 more
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EVIDENCE ON THE BASIS OF THE CENTROMERE EFFECT IN THE LARGE AUTOSOMES OF DROSOPHILA MELANOGASTER [PDF]
, 1964 Peter Thompson
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iMeta, EarlyView.This study presented two high‐precision telomere‐to‐telomere genome assemblies for Min and Rongchang pigs, including a detailed exploration of the telomeric and centromeric regions. By integrating pan‐genome and multi‐omics analyses, structural variations linked to genetic adaptation were identified, providing a valuable resource for advancing pig ...
Wencheng Zong +20 more
wiley +1 more source
THE BEHAVIOR OF STRONG AND WEAK CENTROMERES AT SECOND ANAPHASE OF DROSOPHILA MELANOGASTER [PDF]
, 1960 Mark Ptashne
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