Results 161 to 170 of about 118,231 (380)
CENP-C promotes kinetochore targeting of other constitutive centromere–associated network (CCAN) subunits by directly interacting with the four-subunit CCAN subcomplex CENP-HIKM and spatially organizing the localization of all other CCAN subunits ...
Kerstin Klare+7 more
semanticscholar +1 more source
Dynamics of male meiotic recombination frequency during plant development using Fluorescent Tagged Lines in Arabidopsis thaliana [PDF]
Meiotic homologous recombination plays a central role in creating genetic variability, making it an essential biological process relevant to evolution and crop breeding.
De Storme, Nico, Geelen, Danny, Li, Fan
core +1 more source
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang+9 more
wiley +1 more source
Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core +1 more source
Lactylation in cancer biology: Unlocking new avenues for research and therapy
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou+6 more
wiley +1 more source
Structure of centromere chromatin: from nucleosome to chromosomal architecture
The centromere is essential for the segregation of chromosomes, as it serves as attachment site for microtubules to mediate chromosome segregation during mitosis and meiosis.
T. Schalch, F. Steiner
semanticscholar +1 more source
STUDIES OF A TELOCENTRIC CHROMOSOME IN MAIZE WITH REFERENCE TO THE STABILITY OF ITS CENTROMERE [PDF]
M. M. Rhoades
openalex +1 more source
The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou+6 more
wiley +1 more source