Results 171 to 180 of about 87,751 (339)

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

The FEBS Journal, EarlyView.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar, Siarhei Paliavoi, Barbora Stefanovie, Jan Josef Palecek   +3 more
wiley   +1 more source

Centromere Excision

, 2013
(A) CEN1 on CHRI was replaced with a CEN3-URA3 cassette flanked by head-to-tail-oriented site-specific recombination target sites (red arrows) for the R recombinase from Zygosaccharomyces rouxii, as described in Materials and Methods.
Jennifer L Gerton (26655), Joan E Polancic (26657), Paul C Megee (26650), Stewart A Weber (26656), Joseph L DeRisi (1564), Douglas Koshland (26658)   +5 more
core   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

The Centromere [PDF]

The American Journal of Human Genetics, 1998
Joana Perdigão, Claudio E. Sunkel
openaire   +2 more sources

Centromere Tethering Confines Chromosome Domains

, 2013
The organization of chromosomes into territories plays an important role in a wide range of cellular processes including gene expression, transcription, and DNA repair.
Forest, M. Gregory, Barry, Timothy, Bloom, Kerry, Barry, Raymond Mario, Verdaasdonk, Jolien Suzanne, Vasquez, Paula Andrea, Goodwin, Scott   +6 more
core   +1 more source

Bony fish genomes: Status and gaps

Journal of Fish Biology, EarlyView.
Abstract Bony fish constitute an exceptionally species‐rich group of aquatic vertebrates, comprising more than 95% of all living fish. The adaptive processes on the diversity of environments they inhabit make them a highly diverse group from taxonomic, morphological and evolutionary standpoints.
Noelia Pérez‐Pereira, Carmen Bouza, Paulino Martínez, Diego Robledo   +3 more
wiley   +1 more source

Endogenous Transcription at the Centromere Facilitates Centromere Activity in Budding Yeast

, 2011
SummaryBackgroundThe centromere (CEN) DNA-kinetochore complex is the specialized chromatin structure that mediates chromosome attachment to the spindle and is required for high-fidelity chromosome segregation.
Kentaro Ohkuni, Kitagawa, Katsumi, Katsumi Kitagawa, Ohkuni, Kentaro   +3 more
core   +1 more source

Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate‐resilient apple breeding

Journal of Integrative Plant Biology, EarlyView.
This comprehensive map of genetic variation in wild apple (Malus baccata) and set of key genes associated with adaptation to temperature, precipitation, and soil properties establishes a foundation for breeding climate‐resilient apple cultivars and conserving the genetic resources of wild crop relatives.
Ying Su, Yani Hao, Xuejing Cao, Lin Wang, Zhiqi Xu, Fan Zhang, Zhiyao Ma, Xu Wang, Jiacui Li, Tianrong Fan, Ruoyan Zhao, Zhongqi Liu, Wenrui Wang, Yingchun Zhang, Xuanwen Yang, Sifan Yang, Dajiang Wang, Kun Wang, Simiao Sun, Zichen Li, Wen Tian, Yanming Sun, Zhao Liu, Yanshuai Xu, Hua Xiao, Yanling Peng, Xiaodong Xu, Ruirui Liu, Xinmin Tian, Yongfeng Zhou, Yuan Gao   +30 more
wiley   +1 more source

The higher order structure of the centromere

, 1987
The architecture of the centromere region of mouse chromosomes has been studied in cells grown in the presence of 5-azacytidine. This drug interferes with normal condensation producing elongated centromere regions.
C. C. Lin, J. B. Rattner
core   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source