Results 191 to 200 of about 92,899 (342)

DNA methylome responses to biotic and abiotic stress in Arabidopsis thaliana: A multi‐study analysis

Plant Biology, EarlyView.
Sixteen Arabidopsis thaliana Whole‐Genome Bisulfite Sequencing datasets have been analysed to reveal common and stress‐specific DNA methylation responses. Although global methylation levels remained stable, specific DMRs varied according to the type of stress and genomics context.
R. Behl, J. J. Gallo‐Franco, R. R. Hazarika, Z. Zhang, F. Wilming, J. P. Schnitzler, C. Lindermayr, F. Johannes   +7 more
wiley   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Anti‐Ku positivity in primary Sjögren's disease is associated with a more severe disease course

Journal of Internal Medicine, EarlyView.
Marie Robert, Yann Nguyen, Alain Meyer, Jacques‐Éric Gottenberg, Véronique Le Guern, Pascale Chrétien, Raphaèle Seror, the Anti‐Ku Study Group, Benjamin Terrier, Jérôme Hadjadj, Arnaud Hot, Éléonore Bettacchioli, Yurdagül Uzunhan, Raphaël Borie, Zahir Amoura, François Chasset, Yves Allenbach, Karim Sacré, Cécile Goujard, Elisabeth Aslangul, Bruno Fautrel, Rakiba Belkhir, Frédéric Desmoulins, Elisabeth Bergé, Pascale Roland‐Nicaise, Claire Goulvestre, Jean‐Luc Charuel, Éric Ballot, Benoit Nespola, Frédéric Coutant, Gaétane Nocturne, Xavier Mariette, Samuel Bitoun   +32 more
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Genome‐Wide Analysis of Resistance to Gastrointestinal Parasites in Portuguese Merino and Merino‐Related Sheep

Animal Genetics, Volume 57, Issue 6, December 2026.
ABSTRACT Gastrointestinal nematodes (GIN) are one of the main constraints affecting sheep production worldwide. For decades, control methods based on anthelmintics have been extensively used, which ended up in multiple drug‐resistant helminth strains.
Daniel Gaspar, Catarina Ginja, Nuno Carolino, Célia Leão, Helena Monteiro, Lino Tábuas, Sandra Branco, Pedro Caetano, Ricardo Romão, Claudino Matos, Elisa Bettencourt, António Marcos Ramos, Ana Usié, Ludovina Padre   +13 more
wiley   +1 more source

Challenging White Lesion

Oral Diseases, EarlyView.
Michele Di Benedetto, Izabel Regina Fischer Rubira‐Bullen, Cássia Maria Fischer Rubira, Paulo Sérgio da Silva Santos, Vanessa Soares Lara, Camila Lopes Cardoso   +5 more
wiley   +1 more source

Discovery of a First‐in‐Class Dual‐Function TLX Activator by Microscale Library Synthesis and Direct‐to‐Biology Screening

Angewandte Chemie Novit, Volume 2, Issue 4, December 2026.
The transcription factor tailless (TLX) is an orphan nuclear receptor thought to maintain neural and retinal stem cell populations in a proliferating state to enable regeneration. Ligands to study TLX modulation were lacking. We developed a potent TLX agonist capable of activating TLX's transcriptional repressor and activator properties in an evolution‐
Tanja Stiller, Romy Busch, Giuseppe Faudone, Felia C. Haffelder, Jan Vietor, Arthur Kardanov, Úrsula López‐García, Arne Hackspacher, Georg Höfner, Vasily Morozov, Susanne F. Koch, Julian A. Marschner, Daniel Merk   +12 more
wiley   +1 more source

Correction: Chromodomain mutation in S. pombe Kat5/Mst1 affects centromere dynamics and DNA repair. [PDF]

PLoS One
Li T, Petreaca RC, Park JM, Forsburg SL.
europepmc   +1 more source

Advances in the Integration of Genomic and Phenomic Tools in Cowpea Breeding for Improving Stress Resilience and Grain Yield and Quality

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Cowpea (Vigna unguiculata L. Walp) is a multi‐use crop highly valued as a food crop, high‐protein fodder, and sustainable cover crop. Yet, it remains underused, and yields in most growing regions are below the crop's potential due to multiple biotic and abiotic stresses.
Habib Akinmade, Luis Getino, María Muñoz‐Amatriaín, Esteban Rios   +3 more
wiley   +1 more source

Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple‐negative breast cancer

The Journal of Pathology, Volume 270, Issue 4, Page 507-520, December 2026.
Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification, a significant cancer alteration with both prognostic and therapeutic relevance, lacks a standardized definition. The relationship between FGFR1 copy number (CN) variations and tumour microenvironment (TME) characteristics also remains poorly understood.
Yike Gao, Fei Yao, Junyi Pang, Tianlin Sun, Changbin Zhu, Shafei Wu, Zhiyong Liang   +6 more
wiley   +1 more source