Results 201 to 210 of about 68,825 (297)
MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li +9 more
wiley +1 more source
The enigma of the B chromosome-specific behaviour. [PDF]
Hloušková L +2 more
europepmc +1 more source
The Role of Arp2/3 in End‐Resection During DNA Double‐Strand Break Repair
Arp2/3 has an evolutionarily conserved role in promoting 5’ to 3’ resection of DSBs, RAD51 filament formation, maintenance of the DNA damage checkpoint, increased mobility of DSBs, and relocation of damage in heterochromatin regions to the nuclear periphery.
Felix Y. Zhou, James E. Haber
wiley +1 more source
MCAK/Kif2C centromeric activity level tunes K-fiber turnover through distinct pathways. [PDF]
Wagenbach M, Vicente JJ, Wordeman L.
europepmc +1 more source
The Small but Versatile Cyclin‐Dependent Kinase Subunit CKS
The cyclin‐dependent kinase subunit, CKS, is required for anaphase onset during both meiosis I and II in Caenorhabditis elegans oocytes. One model for how CKS promotes meiosis II anaphase onset involves phosphorylation of a Cullin 2 E3 ligase by CDK/CKS/CYB‐3, followed by the CKS anion pocket binding to the phosphorylated E3, recruiting CDK/CKS/CYB‐1 ...
Jie Yang, Bruce Bowerman
wiley +1 more source
Microtubule-dependent regulation of chromatin dynamics by the Smc5/6 complex. [PDF]
Carré-Simon À +11 more
europepmc +1 more source
STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cervical Adenocarcinoma
STK11 alterations, including mutations, focal deletions, and structural disruption of chromosome 19p, define a distinct molecular subgroup of cervical adenocarcinoma associated with younger age at diagnosis, poorer survival, and reduced benefit from immune checkpoint inhibitors, supporting improved molecular classification and future precision ...
Emma W. Robinson +22 more
wiley +1 more source
First genome-wide centromere map of Trypanosoma cruzi suggests linear and 3D compartment boundaries and spatial clustering. [PDF]
Bellini NK +11 more
europepmc +1 more source
ABSTRACT SLE can rarely present with unilateral pleural effusion or hypertension. A 28‐year‐old woman with loculated exudative pleural effusion was diagnosed with SLE and lupus nephritis fulfilling EULAR/ACR criteria, treated with pigtail drainage, corticosteroids, and hydroxychloroquine, with good recovery.
Amrit Tripathi +4 more
wiley +1 more source
The dynamics of centromere assembly and disassembly during quiescence. [PDF]
Marescal O +4 more
europepmc +1 more source

