Results 221 to 230 of about 68,825 (297)

Clinical and immunological features of rheumatoid arthritis patients with positive anti-centromere antibody: a case-control study. [PDF]

Front Med (Lausanne)
Yan X, Wang M, Ge F, Peng L, Wang X, Wang L.   +5 more
europepmc   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, Volume 5, Issue 3, Page 946-950, September 2026.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

MedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng, Zhipeng Shen, Yuanfang Wu, Xingze Huang, Zhongyuan Zhang, Jiangyu Liu, Qichun Wei, Wenhao Chen, Ye Chen, Liang Xu   +9 more
wiley   +1 more source

Cell-specific Cahn-Hilliard models predict condensed fates of the chromosomal passenger complex. [PDF]

PLoS Comput Biol
Groves SM, Lu MJ, Alvarez-Yela AC, Gerardo-Ramírez M, Stukenberg PT, Lowengrub JS, Janes KA.   +6 more
europepmc   +1 more source

DUSP12 Regulates NAT10‐Mediated RNA Acetylation to Modulate DNA Repair and Therapeutic Response in Hepatocellular Carcinoma

MedComm, Volume 7, Issue 9, September 2026.
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell, Diana Reis Della Corte Guimarães Pacheco, Yuli Thamires Magalhães, Laura Lima Turani, Isabeli Yumi Araújo Osawa, Nicolas Carlos Hoch, Fábio Luís Forti   +6 more
wiley   +1 more source

T2T-Hub: a central platform for analyzing plant and animal telomere-to-telomere genomes. [PDF]

Nucleic Acids Res
Chao H, Ruan Z, Li Z, Zhou X, Zhang S, Shen X, Feng C, Chen D, Chen M.   +8 more
europepmc   +1 more source

Zea mays Drought‐Overly Sensitive1/TUBA4 Is Wilty3, and Transcriptome Co‐Expression Analysis of Shoot Meristem Mutant Tissues Reveals Wilty2/TUB6:Wi3 Interactions Associated With Stem Vascular Bundle Development

Plant Direct, Volume 10, Issue 9, September 2026.
ABSTRACT Plant vasculature is essential for the transport of water, nutrients, and signaling molecules across organs, while also providing critical mechanical support for growth and development. Disruptions in vascular bundle formation can therefore lead to severe physiological and developmental defects.
Anuradha Dhingra, Indra Adhikari, Christopher D. Rock   +2 more
wiley   +1 more source

An improved Solanum verrucosum genome provides insight into potato centromeres and epigenetic regulation. [PDF]

G3 (Bethesda)
Smith M, Kaur A, Singh V, Jones JT, Hein I.   +4 more
europepmc   +1 more source

Speciation with gene flow

PLANTS, PEOPLE, PLANET, Volume 8, Issue 5, Page 1476-1499, September 2026.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long, Xu Zhang, Yue Yu, Gregory L. Owens, Diana J. Rennison, Clarisse Palma‐Silva, Daniel Ortiz‐Barrientos, Loren H. Rieseberg   +7 more
wiley   +1 more source

Prevalence of heterozygous and homozygous 9p21 deletions in human cancer: a tissue microarray study on 4,999 tumors from 125 different tumor types. [PDF]

Mol Med
Gorbokon N, Teljuk K, Schraps N, Lennartz M, Rico SD, Kind S, Reiswich V, Viehweger F, Lutz F, Fraune C, Luebke AM, Menz A, Schlichter R, Krech T, Hinsch A, Burandt E, Sauter G, Simon R, Steurer S, Marx AH, Lebok P, Dum D, Minner S, Jacobsen F, Clauditz TS, Hackert T, Uzunoglu FG, Bernreuther C, Kluth M.   +28 more
europepmc   +1 more source