Results 231 to 240 of about 92,899 (342)

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, Volume 78, Issue 11, Page 1650-1662, November 2026.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

A complete reference genome reveals genetic landscape of Brassica centromeres. [PDF]

Genome Biol
Xu XD, Ye SY, Wu P, Qian YQ, Zhou ZW, Chai Y, Feng Z, Tan Y, Xiang J, Wei L, Wang R, Zhou Q, Qu C, Li J, Chen LL, Lu K, Song JM.   +16 more
europepmc   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2365-2377, November 2026.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

EasyCen: A Lightweight Framework for Centromere Localisation and Repeat-Organisation Profiling in Telomere-to-Telomere Genomes. [PDF]

Mol Ecol Resour
Lv Y, Li Y, Li J, Mu X.
europepmc   +1 more source

Association of M18BP1/KNL2 with CENP-A Nucleosome Is Essential for Centromere Formation in Non-mammalian Vertebrates.

Developmental Cell, 2017
T. Hori, Wei H. Shang, Masatoshi Hara, M. Ariyoshi, Y. Arimura, R. Fujita, H. Kurumizaka, T. Fukagawa   +7 more
semanticscholar   +1 more source

Genome‐wide association study reveals the genetic architecture of five grain minerals in North American spring wheat (Triticum aestivum L.)

Crop Science, Volume 66, Issue 6, November/December 2026.
Abstract Biofortification aims to reduce the prevalence of micronutrient malnutrition in vulnerable populations by breeding staple crops with an increase in nutrient density. Assessing the phenotypic variation of grain minerals and their genetic control under common management practices can provide a strong foundation for nutrition‐related trait ...
Emily F. Klarquist, Aichatou D. Waziri, Kimberly Garland‐Campbell, Michael Pumphrey   +3 more
wiley   +1 more source

A global view of human centromere variation and evolution. [PDF]

Nature
Gao S, Oshima KK, Chuang SC, Loftus M, Potapova TA, Montanari A, Gordon DS, Yang Z, Human Genome Structural Variation Consortium, Human Pangenome Reference Consortium, Mao Y, Hsieh P, Gerton JL, Konkel MK, Ventura M, Logsdon GA.   +15 more
europepmc   +1 more source

The Role of Chromosomal Fusions in Genetic Divergence of a Keystone Arctic Species (Boreogadus saida)

Ecology and Evolution, Volume 16, Issue 11, November 2026.
Although much focus has been given to the importance of chromosome inversions in harboring adaptive alleles in non‐model species, there are other mechanisms that can facilitate divergence. Here we utilize whole genome sequence data from Arctic cod (Boreogadus saida) to investigate patterns of adaptive divergence in a system with high gene flow. We find
Matthew C. Hale, Natasha Howe, Tracey Loewen, Kevin Hedges, Maxime Geoffroy, Jennifer L. Herbig, Wes Larson   +6 more
wiley   +1 more source

Probing Centromere Plasticity and Chromatin Remodeling Using Single-Molecule Techniques. [PDF]

Cell Biol Int
Liu R, Zhao J, Ma H, Hu W, Dou Z, Liu X.
europepmc   +1 more source

Complex and Cryptic KMT2A::MLLT10 Rearrangements in Acute Myeloid Leukemia Resolved by Optical Genome Mapping

Genes, Chromosomes and Cancer, Volume 65, Issue 11, November 2026.
ABSTRACT Accurate identification of KMT2A::MLLT10 fusions is essential for diagnostic classification and prognostication in acute myeloid leukemia and can guide therapeutic decision making. Detection of these fusions is diagnostically challenging due to the frequently cryptic and structurally complex nature of these events.
Fatma AlBulushi, Nicolas Salcedo‐Porras, Julia N. C. Parlow, Christine Nast, Zeid Hamadeh, Dan Li, Tara Spence, Eric McGinnis   +7 more
wiley   +1 more source