Results 191 to 200 of about 26,352 (303)

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source

DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres

open access: yesNature Cell Biology, 2019
Yael Nechemia-Arbely   +9 more
semanticscholar   +1 more source

TRAPPC2l Participates in Male Germ Cell Development by Regulating Cell Division

open access: yesCell Proliferation, EarlyView.
Trappc2l is crucial for maintaining the quiescent state of male gonocytes. In the absence of Trappc2l, the quiescent state of gonocytes is disrupted, leading to premature and abnormal initiation of meiosis, which consequently results in subsequent abnormalities in sperm development. ABSTRACT TRAPPC2L is a core subunit of the Transport Protein Particle (
Mengyue Wang   +8 more
wiley   +1 more source

The molecular basis for centromere identity and function

open access: yesNature reviews. Molecular cell biology, 2015
Kara L. McKinley, I. Cheeseman
semanticscholar   +1 more source

Cpf1 protein induced bending of yeast centromere DNA element I [PDF]

open access: green, 1993
Rainer Niedenthal   +3 more
openalex   +1 more source

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