Results 201 to 210 of about 118,231 (380)

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam   +12 more
wiley   +1 more source

Taxonomy and dated molecular phylogeny of Allium oreophilum sensu lato (A. subg. Porphyroprason) uncover a surprising number of cryptic taxa

open access: yesTAXON, EarlyView.
Abstract Allium oreophilum, hitherto the representative of the monotypic A. subg. Porphyroprason from the second evolutionary lineage of Allium, is studied in detail. Over about 150 years, A. oreophilum was regarded as a somewhat polymorphous species with two synonyms, all described in the 19th century.
Nikolai Friesen   +13 more
wiley   +1 more source

A molecular cytogenetic perspective on chromosome biology and crop improvement. [PDF]

open access: yesPlant Genome
Abstract The age of molecular cytogenetic analysis of crop plants dawned in the late 1960s and early 1970s with new advances in the identification of somatic chromosomes by C‐banding and fluorescence in situ hybridization concurrent with advances in DNA cloning, sequencing, and mapping. In this perspective article dedicated to Ronald Phillips, I review
Gill BS.
europepmc   +2 more sources

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

open access: yesInsect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn   +8 more
wiley   +1 more source

Comparative Satellitomics in Arowanas (Telostei, Osteoglossiformes) Sheds Light on the Evolution of Ancient Satellite DNAs

open access: yesIntegrative Zoology, EarlyView.
This work focused on arowana fishes (Teleostei, Osteoglossiformes) as a model; their widespread intercontinental distribution and basal phylogenetic position within Teleostei make them a compelling model for evolutionary research, especially in the realm of satDNA molecular evolution. Through the integration of genomic and chromosomal data, we analyzed
Fernando Henrique Santos de Souza   +9 more
wiley   +1 more source

Comparative Analyses of Four Reference Genomes Reveal Exceptional Diversity and Weak Linked Selection in the Yellow Monkeyflower (Mimulus guttatus) Complex

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Yellow monkeyflowers (Mimulus guttatus complex, Phrymaceae) are a powerful system for studying ecological adaptation, reproductive variation, and genome evolution. To initiate pan‐genomics in this group, we present four chromosome‐scale assemblies and annotations of accessions spanning a broad evolutionary spectrum: two from a single M ...
John T. Lovell   +21 more
wiley   +1 more source

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