Results 241 to 250 of about 88,605 (330)

CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin   +7 more
wiley   +1 more source

Rare Chromosomal Uniformity in Black Flies of the <i>Simulium striatum</i> Species Group (Diptera: Simuliidae). [PDF]

open access: yesInsects
Adler PH   +15 more
europepmc   +1 more source

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

open access: yesCytoskeleton, Volume 82, Issue 6, Page 372-387, June 2025.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith   +9 more
wiley   +1 more source

An Incidental Finding of Gain of a Diminished Chromosome 12 Centromere in an Individual with Lymphocytosis: A Case Report and Clinical Implications in Cytogenetic Testing. [PDF]

open access: yesDiagnostics (Basel)
Xia C   +11 more
europepmc   +1 more source

Analysis of Treatment and Subsequent Pregnancy Outcomes in Patients With Antinuclear Antibody‐Positive Recurrent Spontaneous Abortion

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 6, June 2025.
ABSTRACT Background The etiology of recurrent spontaneous abortion (RSA) has not been clearly defined. The role of autoantibodies in RSA has particularly attracted much attention. Objective A retrospective analysis was performed to explore the combinatory efficacy of five drugs (aspirin enteric‐coated tablets, hydroxychloroquine sulfate ...
Ancong Wang   +5 more
wiley   +1 more source

Independence of centromeric and pericentromeric chromatin stability on CCAN components. [PDF]

open access: yesMol Biol Cell
Biggs RJ   +5 more
europepmc   +1 more source

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