Results 171 to 180 of about 28,742 (199)

Dynamic Mitotic Localization of the Centrosomal Kinases CDK1, Plk, AurK, and Nek2 in Dictyostelium amoebae. [PDF]

Cells
Krüger S, Pfaff N, Gräf R, Meyer I.
europepmc   +1 more source

NE-MTOC Formation in Skeletal Muscle Is Mbnl2-Dependent and Occurs in a Sequential and Gradual Manner. [PDF]

Cells
Das P, Becker R, Vergarajauregui S, Engel FB.   +3 more
europepmc   +1 more source

Emerin preserves stem cell survival through maintenance of centrosome and nuclear lamina structure.

Development
Jones SD, Miller JEB, Amos MM, Hernández JM, Piaszynski KM, Geyer PK.   +5 more
europepmc   +1 more source

Maintenance of niche architecture requires actomyosin and enables proper stem cell signaling and oriented division in the Drosophila testis.

Development
Vida GS, Botto E, DiNardo S.
europepmc   +1 more source

Microtubule pivoting driven by spindle elongation rescues polar chromosomes to ensure faithful mitosis

Tolić I, Koprivec I, Stimac V, Mikec P.
europepmc   +1 more source

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Centrosomal and non‐centrosomal microtubules

Biology of the Cell, 1999
While microtubule (MT) arrays in cells are often focused at the centrosome, a variety of cell types contain a substantial number of non‐centrosomal MTs. Epithelial cells, neurons, and muscle cells all contain arrays of non‐centrosomal MTs that are critical for these cells' specialized functions. There are several routes by which non‐centrosomal MTs can
Thomas J. Keating, Gary G. Borisy
openaire   +5 more sources

Aurora A, centrosome structure, and the centrosome cycle

Environmental and Molecular Mutagenesis, 2009
AbstractThe centrosome, also known as the microtubule organizing center of the cell, is a membrane‐less organelle composed of a pair of barrel‐shaped centrioles surrounded by electron‐dense pericentriolar material. The centrosome progresses through the centrosome cycle in step with the cell cycle such that centrosomes are duplicated in time to serve as
Kara Lukasiewicz, Wilma L. Lingle
openaire   +3 more sources

Centrosomes and cancer

Biology of the Cell, 1999
The centrosome functions as the major microtubule organizing center (MTOC) of the cell and as such it determines the number, polarity, and organization of interphase and mitotic microtubules. Cytoplasmic organization, cell polarity and the equal partition of chromosomes into daughter cells at the time of cell division are all dependent on the normal ...
Wilma L. Lingle, Susan L. Barrett, Clark M. Whitehead, Jeffrey L. Salisbury   +3 more
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Centrosomes and Centrosome Equivalents in Other Systems

2022
Stem cells are important to sustain tissue growth during development, to repair damaged tissue after injury, and to maintain homeostasis during adulthood. Precisely programmed stem cell renewal and differentiation is critical, as failure in balance can lead to tumorigenesis as a result of over-proliferation or to degeneration as a result of decline in ...
openaire   +2 more sources

Centrosome instability: when good centrosomes go bad

Cellular and Molecular Life Sciences, 2021
The centrosome is a tiny cytoplasmic organelle that organizes and constructs massive molecular machines to coordinate diverse cellular processes. Due to its many roles during both interphase and mitosis, maintaining centrosome homeostasis is essential to normal health and development. Centrosome instability, divergence from normal centrosome number and
John M. Ryniawec, Gregory C. Rogers
openaire   +3 more sources