Results 51 to 60 of about 104,609 (288)

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

MICROBIOLOGICAL ASSAY FOR THE DETERMINATION OF CEFPIROME IN RAW MATERIAL AND INJECTABLE PREPARATION

Drug Analytical Research, 2018
Cefpirome is a fourth-generation cephalosporin active against a broad spectrum of gram-negative and gram-positive bacterial infections. The present work describe the development and validation of a simple, sensitive and specific agar diffusion bioassay ...
Tércio Paschke Oppe, Julia Menegola, Elfrides E.S. Schapoval   +2 more
doaj   +1 more source

Detection of extended-spectrum beta-lactamase genes in members of the Proteeae tribe isolated from a tertiary hospital in Southeast, Nigeria

Nigerian Journal of Medicine, 2022
Background: Tribe Proteeae consisting of Proteus, Providencia, and Morganella species are critical opportunistic pathogens causing various health care-associated infections.
Comfort Nne Akujobi, Chinenye Vivian Okwesilieze, Iloduba Nnaemeka Aghanya, Solomon Nwabueze Ukibe, Akachukwu Egwu Okoro, Simon Nkpeh Ushie, Nkechi Perpetua Maduekwe   +6 more
doaj   +1 more source

Effect of Broad‐Spectrum Antibiotic Prophylaxis on Post‐Pancreatoduodenectomy Infectious Complications: Nationwide Inpatient Database Study in Japan

Annals of Gastroenterological Surgery, EarlyView.
Using a nationwide Japanese inpatient database, we evaluated whether broad‐spectrum antibiotic prophylaxis improves postoperative outcomes after pancreatoduodenectomy compared with narrow‐spectrum antibiotics. In propensity score–weighted analyses of 45 099 patients, broad‐spectrum prophylaxis was associated with significantly lower rates of intra ...
Hiroki Kitagawa, Shotaro Aso, Yuki Hirano, Kenichiro Uemura, Keita Kouzu, Satoru Matsuda, Hiroki Matsui, Kiyohide Fushimi, Junichi Sasaki, Yuko Kitagawa, Hideo Yasunaga   +10 more
wiley   +1 more source

Comparative analysis of the pathogenicity between multidrug-resistant Acinetobacter baumannii clinical isolates: isolation of highly pathogenic multidrug-resistant A. baumannii and experimental therapeutics with fourth-generation cephalosporin cefozopran

Infection and Drug Resistance, 2018
Satoshi Nishida, Yasuo Ono Department of Microbiology and Immunology, Teikyo University School of Medicine, Itabashi, Tokyo, Japan Introduction: The pathogenicity of fatal-outbreak Acinetobacter baumannii isolates has not been fully investigated.
Nishida S, Ono Y
doaj  

Synthesis and Total 1H- and 13C-NMR Assignment of Cephem Derivatives for Use in ADEPT Approaches

Molecules, 2008
We report the synthesis and total NMR characterization of 5-thia-1-azabicyclo-[4.2.0]oct-2-ene-2-carboxylic acid-3-[[[(4’’-nitrophenoxy)carbonyl]oxy]-methyl]-8-oxo-7-[(2-thienyloxoacetyl)amino]-diphenylmethyl ester-5-dioxide (5), a new ...
Man-Chin Chung, Vladimir Constantino Gomes Heleno, Leila Aley Tavares, Elisangela Fabiana Boffo, Antonio Gilberto Ferreira, Elizabeth Igne Ferreira, Renato Farina Menegon, Lorena Blau   +7 more
doaj   +1 more source

Post Penicillin Antibiotics: From acceptance to resistance? [PDF]

, 2000
Edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, in London, on 12 May 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Reynolds, LA, Tansey, EM
core  

Impaired clearance of ceftizoxime and cefotaxime after orthotopic liver transplantation. [PDF]

, 1987
The pharmacokinetics of ceftizoxime (CZX) and of cefotaxime (CTX) were studied in five children and five adults after orthotopic liver transplantation (OLT).
Burckart, GJ, Howrie, DL, Jones, DH, Ptachcinski, RJ, Starzl, TE, Venkataramanan, R   +5 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Effect of Antimicrobial Exposure in Pregnancy on Adverse Pregnancy Outcomes and Admission Rate to the Neonatal Intensive Care Unit: A Multi-Center Cohort Study

Infection and Drug Resistance, 2023
Yueyan Li,1 Chen Zhang,2 Xuan Huang,1 Jing Tang1 1Department of Pharmacy, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China; 2Institute of Reproduction and Development, Obstetrics and Gynecology Hospital of ...
Li Y, Zhang C, Huang X, Tang J
doaj