Results 181 to 190 of about 338,348 (241)

Structural basis of the mechanism and inhibition of a human ceramide synthase

, 2023
Pascoa TC, Pike AC, Tautermann CS, Chi G, Traub M, Quigley A, Chalk R, Štefanic S, Thamm S, Pautsch A, Carpenter EP, Schnapp G, Sauer DB.   +12 more
europepmc   +1 more source

Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway. [PDF]

Leukemia, 2022
Sofi MH, Tian L, Schutt S, Khan I, Choi HJ, Wu Y, Bastian D, Ticer T, Kassir MF, Atilgan FC, Kim J, Sui X, Zivkovic A, Mehrotra S, O'Bryan JP, Stark H, Martin PJ, Ogretmen B, Yu XZ.   +18 more
europepmc   +1 more source

Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia.

, 2001
Microglia, brain inflammatory cells, are activated in injured brain and function similar to macrophages. The activated microglia produce nitric oxide (NO), a major toxic substance from these cells, by inducing expression of inducible NO synthase (iNOS ...
Joe, E, Yang, MS, Jou, I, Inn-Oc, H
core  

KLF9 Inhibits Brain Metastasis of Non-Small Cell Lung Cancer by Regulating Ceramide Synthase 1 Synthesis. [PDF]

FASEB J
He Y, Pan J, Chen S, Lin Y, She P, Chen Y, Xu N, Li H.   +7 more
europepmc   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

The lipidomes of <i>C. elegans</i> with mutations in <i>asm-3</i>/acid sphingomyelinase and <i>hyl-2</i>/ceramide synthase show distinct lipid profiles during aging. [PDF]

Aging (Albany NY), 2023
Staab TA, McIntyre G, Wang L, Radeny J, Bettcher L, Guillen M, Peck MP, Kalil AP, Bromley SP, Raftery D, Chan JP.   +10 more
europepmc   +1 more source

Ceramide and apoptosis

, 1999
Ceramide is a sphingosine-based lipid second messeger molecule that is involved in regulation of differentiation, proliferation, apoptosis, or growth arrest.
Centi, C, Cifone, MG, DI MARZIO, Luisa
core  

Ursodeoxycholic acid alleviates aortic aneurysm and dissection through the intestinal farnesoid X receptor/ceramide synthase 2 axis. [PDF]

Commun Biol
Zhang Z, Xie L, Lin X, He J, Xie Y, Li J, Zhuang X, Tang L, Xie R, Wu Q, Qiu Z, Chen L.   +11 more
europepmc   +1 more source

A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis

The FASEB Journal, 2018
Bianca Williams, Jason M. Correnti, Amanke C. Oranu, Annie Lin, Victoria Scott, Maxine Annoh, James Beck, E. Furth, Victoria S. Mitchell, C. Senkal, L. Obeid, R. Carr   +11 more
semanticscholar   +1 more source

Ceramide Synthase 2 Promotes Cardiac Very-Long-Chain Dihydroceramide Accumulation and Is Linked to Arrhythmias and Heart Failure in Humans. [PDF]

Int J Mol Sci
Andersson L, Cinato M, Björnson E, Lundqvist A, Miljanovic A, Henricsson M, Bergh PO, Adiels M, Jeppsson A, Borén J, Levin MC.   +10 more
europepmc   +1 more source