Results 111 to 120 of about 32,676 (287)
Influenza A Virus Infection Induces Preferential Increases in Long-Chain Ceramides. [PDF]
VirusesInfluenza is a persistent public health concern worldwide. The elucidation of influenza A virus (IAV)–host interactions and the identification of host factors that regulate IAV infection would be beneficial for combating and treating the disease ...
McKenna S +5 more
europepmc +2 more sources
The Oncologic Ambivalence of Longevity Interventions in Photoaged Skin
JEADV Clinical Practice, EarlyView.This graphical abstract presents a stage‐dependent framework for longevity interventions in photoaged skin. UV exposure drives progression from photodamage to field cancerization and skin cancer. Systemic interventions may modulate stress‐response pathways throughout the body, whereas energy‐based procedures generate spatially confined responses ...
Erik Senger, Lea Kurzen, Hjalmar Kurzen
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley +1 more source
The ART of Lowering Ceramides [PDF]
Cell Metabolism, 2015 Ceramides are lipid metabolites implicated in the metabolic dysregulation that accompanies dyslipidaemia and obesity. Using a genetic mouse model to acutely degrade ceramides in adipose tissue or the liver (i.e., by conditionally expressing acid ceramidase), in this issue of Cell MetabolismXia et al. (2015) identify roles for these molecules in insulin
openaire +2 more sources
, 2016 In the outermost layer of the skin, the stratum corneum (SC), ceramides form a diverse and essential pool of lipids. Due to their diversity and the limited availability of synthetic standards it is challenging to quantitatively analyse all SC ceramides
Bouwstra, J. +4 more
core +1 more source
Synthesis of ceramides using N-hydroxysuccinimide esters
Journal of Lipid Research, 1972 Fatty acyl esters of N-hYdroxYSuccinimide have been used to directly N-acylate sphingenine or sphinganine, forming the corresponding ceramides. The reaction proceeds in excellent yield (84–96%) from small amounts of starting material (10–20 mg).
David E. Ong, Robert N. Brady
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Metabolic Messengers: ceramides
Nature Metabolism, 2019 Ceramides are products of metabolism that accumulate in individuals with obesity or dyslipidaemia and alter cellular processes in response to fuel surplus. Their actions, when prolonged, elicit the tissue dysfunction that underlies diabetes and heart disease.
Scott A. Summers +2 more
openaire +3 more sources
Synthesis and study of O- and N-modified ceramides [PDF]
, 2014 Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Candidate: Ludmila Pavlíková Supervisor: doc. PharmDr. Kateřina Vávrová, Ph.D.
Pavlíková, Ludmila
core
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source