Results 101 to 110 of about 31,716 (293)

Ceramide in Stress Response [PDF]

open access: yes, 2010
Evidence has consistently indicated that activation of sphingomyelinases and/or ceramide synthases and the resulting accumulation of ceramide mediate cellular responses to stressors such as lipopolysaccharide, interleukin 1beta, tumor necrosis factor alpha, serum deprivation, irradiation and various antitumor treatments.
Nikolova-Karakashian, Mariana N.   +1 more
openaire   +2 more sources

Synthesis of ceramides using N-hydroxysuccinimide esters

open access: yesJournal of Lipid Research, 1972
Fatty acyl esters of N-hYdroxYSuccinimide have been used to directly N-acylate sphingenine or sphinganine, forming the corresponding ceramides. The reaction proceeds in excellent yield (84–96%) from small amounts of starting material (10–20 mg).
David E. Ong, Robert N. Brady
doaj   +1 more source

Interaction of ceramides and tear lipocalin [PDF]

open access: yes, 2018
The distribution of lipids in tears is critical to their function. Lipids in human tears may retard evaporation by forming a surface barrier at the air interface.
Glasgow, Ben J   +3 more
core   +1 more source

Synthesis and study of ceramides with deuterated acyl chain [PDF]

open access: yes, 2014
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Inorganic and Organic Chemistry Candidate: Klára Hudská Supervisor: Doc. PharmDr. Kateřina Vávrová, Ph.D.
Hudská, Klára
core  

Progress in the analysis of stratum corneum ceramides

open access: yes, 2004
The stratum corneum with its unique structure of corneocytes and intercellular lipid lamellae enables a protection of human and other mammalian skin against transepidermal water loss and harmful substances from the environment.
Neubert, Reinhard HH   +3 more
core   +1 more source

The long and the short of ceramides [PDF]

open access: yesJournal of Biological Chemistry, 2018
The sphingolipid ceramide is not only a precursor of more complex sphingolipids, but also a potent signaling molecule. Specific ceramide species have distinct cellular functions, and each ceramide synthase therefore has particular roles in cells and organisms.
openaire   +2 more sources

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Novel ceramides and a new glucoceramide from the roots of Incarvillea arguta

open access: yes, 2004
Novel ceramides, rel-(3S,4S,5S)-3-[(2R)-2-hydroxycosanoylsimilar tohexacosanoylamino]-4-hydroxy-5-[(4Z)-tetradecane- 4-ene]-2,3,4,5-tetrahydrofuran (1a-g), and a new glucoceramide, 1-O-beta-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2R)-2-hydroxytetracosanoylam ...
Zhang, GL, Chinese Acad Sci, Chengdu Inst Biol, POB 416, Chengdu 610041, Peoples R China.   +4 more
core  

Multivariate analysis of pre vs. post biopsies and ceramides distribution.

open access: yes, 2016
(A) OPLS-DA score plot visualizing the grouping of pre vs. post for all biopsies. (B) S-plot illustrating ceramides correlation to groups for model in A.
Wayel Jassem (739666)   +9 more
core   +1 more source

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