Results 151 to 160 of about 41,371 (294)

Cold‐Induced Lipidomic Remodelling Is Associated With Brown Adipose Tissue Mean Radiodensity in Humans

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang, Borja Martinez‐Tellez, Alida Kindt, Nicolas Drouin, Amy Harms, Thomas Hankemeier, Jonatan R. Ruiz, Lucas Jurado‐Fasoli   +7 more
wiley   +1 more source

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

The FEBS Journal, EarlyView.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump, Leja Perne, Špela Koren, Eva Jarc Jovičić, Nastja Feguš, Carina Pinto Kozmus, Michele Wölk, Kristyna Brejchova, Maria Fedorova, Ondrej Kuda, Toni Petan   +10 more
wiley   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Detergents without a drain: the evolutionary logic (and liability) of sphingolipids. [PDF]

J Lipid Res
Summers SA.
europepmc   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

Lipidomics reveals the pro-viral roles of ceramides during fish nodavirus infection. [PDF]

J Virol
Zhang Y, Liu L, Lin L, Zhao Y, Xi K, Guo X, Qin Q, Huang X, Huang Y.   +8 more
europepmc   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

A Reproducible Ceramide Phenotype of Sepsis Across Aetiologies - A Monocenter Cohort Study. [PDF]

J Inflamm Res
Pavel V, Mester P, Höring M, Krautbauer S, Liebisch G, Schmid S, Müller M, Buechler C.   +7 more
europepmc   +1 more source

A serum and cream moisturization regimen outperforms separate use in sustaining hydration, reducing TEWL, and balancing surface lipids over an 8‐h study

International Journal of Cosmetic Science, EarlyView.
Over 8 h, using a Hyaluronic Acid Serum in combination with a Moisturizing Cream sustained skin hydration more than either product alone, while lowering TEWL and normalizing surface lipids. Volunteers also reported a more immediate and long‐lasting moisturization with the combined regimen. Created in BioRender. Maldonado Lopez, A.
Alexandra M. Maldonado López, Ivan Domicio da Silva Souza   +1 more
wiley   +1 more source

Improvement of Overall Skin Condition in Acne and Oily Prone Skin With an Amino Acid Cleanser Containing Salicylic Acid, Glucuronolactone, and Ceramides. [PDF]

J Cosmet Dermatol
Ai Levin Y, Lyu Y, He X.
europepmc   +1 more source