Results 171 to 180 of about 31,716 (293)

Liver-derived ceramides link metabolism to tissue wasting in cancer cachexia. [PDF]

J Clin Invest
Huang K, Perrimon N, Goncalves MD.
europepmc   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Ceramide: a pivotal lipid mediator shaping female reproductive homeostasis and pathophysiology. [PDF]

J Ovarian Res
Wang W, Zhang F, Huang L, Qiao J, Qi X.
europepmc   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Ceramides in the Heart: Physiological and Pathological Roles and Regulation. [PDF]

Cells
Chen X, Fonseka O, Han Y, Liu W.
europepmc   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Antitumor Activity of Liposomal Nanoparticles Co-Encapsulating Ceramides and Doxorubicin in In Vitro Nucleolin-Expressing Neuroblastoma Models. [PDF]

Cells
Bensa V, Lopes-Cardoso H, Ardito M, Ciampi E, Voronovska A, Soares-Gonçalves J, Ponzoni M, Brignole C, Moreira JN, Pastorino F.   +9 more
europepmc   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

MR Derived Cardiac Metabolism Changes in Patients With Obesity and Diabetes: Knowledge Discovery Via Bayesian Networks and Random Forest Classification

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Characterization of healthy vs. diabetic (73:67$$ 73:67 $$) random forest classification group and its Bayesian network learned through NOTEARS structure algorithm on multi‐modal data. Shown computed SHapley Additive exPlanation (SHAP) values for various features.
Ina Hanninger, Andrej Krafčík, Eylem Levelt, Jennifer J Rayner, Chistopher T Rodgers, Stefan Neubauer, Vicente Grau, Oliver J Rider, Ladislav Valkovič   +8 more
wiley   +1 more source

Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits? [PDF]

J Am Soc Nephrol
Saum KL, Pennathur S.
europepmc   +1 more source