Cytosolic lipid trafficking proteins STARD4 and STARD5 modulate hepatic neutral lipid metabolism: implications for diabetic dyslipidaemia and steatosis [PDF]
, 2015 Dolan, Sharron +2 more
core +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
Obesity Reviews, EarlyView.ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Cassava (Manihot esculenta Crantz) exhibits exceptional tolerance to infertile soils and contains abundant cyanogenic glucosides (CGs). Previous research has indicated that CGs can serve as a significant reservoir of organic nitrogen in plants.
Weitao Mai +10 more
wiley +1 more source
Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management. [PDF]
J DermatolSakai T.
europepmc +1 more source
Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids [PDF]
, 2017 Abumrad, Nada A. +2 more
core +2 more sources
The State of Prevention of Atopic Dermatitis: An Updated Review
Pediatric Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder that has a high worldwide prevalence and carries substantial psychosocial and financial burden. As such, the prevention of AD is an important area of research. In this review, we provide an update synthesizing relevant clinical trials published from January 2020 through July 2025 ...
Alexandra Kiszluk, Peter Lio
wiley +1 more source
Beyond antifungals: vaginal ceramides as a barrier-restorative strategy for recurrent vulvovaginal candidiasis in Ehlers-Danlos syndrome. [PDF]
Ann Med Surg (Lond)Amjad M +4 more
europepmc +1 more source
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
Reversing the effects of ceramide imbalance via anti-ceramide immunotherapy is an effective therapy for diabetic retinopathy. [PDF]
Cell Death DiscovZhou L, Li J, Fu C, Chu WK.
europepmc +1 more source