Results 161 to 170 of about 31,716 (293)

The role of ceramides in the pathophysiology of diabetic retinopathy: Mechanisms and Implications for therapeutic strategies. [PDF]

Diab Vasc Dis Res
Niu X, Huang Y, Sun C, Huo Y, Fu K, Yu S, Wang T, Liu J, Pu W, Hu J, Ren L.   +10 more
europepmc   +1 more source

Illuminating Connections: Exploring the Dynamic Relationship Between Phototherapy and the Skin

Pediatric Dermatology, EarlyView.
ABSTRACT The neonatal period represents a critical window for skin barrier maturation, microbial colonization, and immune development. As such, early‐life exposures may exert lasting effects on dermatologic and systemic health. A common early‐life exposure is blue light phototherapy (BLP), a life‐saving treatment for neonatal hyperbilirubinemia ...
Meshi Paz, Peter Lio
wiley   +1 more source

The riddle of sphingolipid structure-function relationship in the nervous system. [PDF]

J Biol Chem
Muñoz-Gil S, Spassieva SD.
europepmc   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Caloric restriction improves glycemic control via the adiponectin-ceramide axis in non-obese men and women: the CALERIE™ 2 randomized controlled trial. [PDF]

Nat Commun
Warmbrunn MV, Biswas RK, Don AS, Lastra Cagigas M, Li Y, Yang L, Twigg SM, Fiorito G, Fontana L.   +8 more
europepmc   +1 more source

Platelet‐activating factor‐receptor signaling mediates solar‐simulated light‐induced extracellular vesicle release in human keratinocytes

Photochemistry and Photobiology, EarlyView.
Solar‐simulated light (SSL) promotes extracellular vesicle (EV) release from keratinocytes through a UVB‐driven, oxidative stress‐dependent pathway. SSL‐induced reactive oxygen species (ROS) generate oxidized glycerophosphocholines with PAF agonistic activity, which activate the Platelet‐activating factor receptor (PAFR), leading to acid ...
Divyanshu Aggarwal, Anita Thyagarajan, Michael G. Kemp, Ravi P. Sahu   +3 more
wiley   +1 more source

Ceramides and Type 2 Diabetes: A Scoping Review of Mechanisms, Insulin Resistance, and Nutritional Interventions. [PDF]

Cureus
Collins K, Chawla J, Krishnakumar P.
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Apical proximal tubule fatty acid uptake-generated ceramides cause endoplasmic reticulum stress from altered membrane fluidity. [PDF]

JCI Insight
Liu Z, Gaivin RJ, Khan S, Li V, Chaba A, Moss FJ, Sabir U, Kasumov T, Mu T, Schelling JR.   +9 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source