Results 161 to 170 of about 32,676 (287)

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Association between dietary fatty acids and all‐cause mortality in patients with cirrhosis: A cohort study

Experimental Physiology, EarlyView.
Abstract Liver cirrhosis imposes a substantial global burden, with complications driving high mortality. Diet is pivotal in managing liver disease progression and cirrhosis‐related death. This study investigated associations between total fat intake, specific dietary fatty acid subclasses and all‐cause mortality in cirrhotic patients.
Ali Jafari, Ghazaleh Mahdavi‐Mazdeh, Behnaz Narimani, Helia Mardani, Azita Hekmatdoost, Fereshteh Pashayee‐Khamene, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Zahra Yari   +10 more
wiley   +1 more source

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source

Implementation of Nano Flow Chromatography Coupled to Mass Spectrometry as a Reliable and Sensitive Discovery Lipidomics Platform

Rapid Communications in Mass Spectrometry, Volume 40, Issue 23, 15 December 2026.
ABSTRACT Rationale Untargeted lipidomics is commonly performed at analytical flow rates, which consume more solvent and may require higher on‐column sample loads when sensitivity is limited by analyte abundance. Nano flow separations use lower flow rates and sample loads, reducing solvent consumption and facilitating improved electrospray ionization ...
Ciara J. Sallowicz, Thiago Mattos, Rahul R. Deshpande, Bashar Amer, Susan S. Bird   +4 more
wiley   +1 more source

Circulating Plasma Adiposomes as a Partial Lipidomic Readout of Matched Subcutaneous Adipose Tissue: Implications for Interorgan Communication

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
In 22 participants, circulating plasma adiposome lipidomes showed moderate global concordance with matched subcutaneous adipose tissue adiposomes across 773 lipid features and 18 classes. These findings support plasma adiposomes as accessible, non‐invasive biomarkers of adipose lipid biology while recognizing compartment‐specific differences.
Mohamed Saad Rakab, Imaduddin Mirza, Elsayed Metwally, Mohammed Morsy, Carlos Martinez, Mario Masrur, Chandra Hassan, Francesco M. Bianco, Brian T. Layden, Abeer M. Mahmoud   +9 more
wiley   +1 more source

Metabolomics Reveals Multiple Metabolic Alterations and Biomarkers of Disease Severity in Facioscapulohumeral Muscle Dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is one of the most common adult‐onset myopathies and is causally associated with a contraction of the D4Z4 macrosatellite repeat array on chromosome 4. It presents with a variable pattern of progressive muscle weakness affecting the face, shoulder girdle and lower limbs ...
Pascal Reynier, Mathieu Michel, Patrick Vandeputte, Noemi Albano, Dario Zoppi, Charlène Gillet, Sara Pini, Andi Nuredini, Martina De Maria, Odile Blanchet, Naig Gueguen, Juan Manuel Chao de la Barca, Lucia Ruggiero, Rossella Tupler, Marco Spinazzi   +14 more
wiley   +1 more source

Farnesoid X Receptor Agonist INT‐787 Protects Human Liver Organoids From Alcohol‐Induced Injury

Liver International Communications, Volume 7, Issue 4, December 2026.
ABSTRACT Background Alcohol‐associated liver disease (ALD) represents a spectrum of liver injury ranging from steatosis to alcohol‐associated hepatitis, cirrhosis, and hepatocellular carcinoma. Activation of the farnesoid X receptor (FXR) decreases liver steatosis, inflammation, and fibrosis in animal models of liver‐related diseases, including ...
Francesca De Franco, Gianmario Ciaccioli, Marco Cipolloni, Carolina Colliva, Sanjay Kansra, Luciano Adorini, Roberto Pellicciari, Mary Erickson, Daniela Passeri   +8 more
wiley   +1 more source

Ceramide in Rice Grain [PDF]

Agricultural and Biological Chemistry, 1975
KONDO, Yasuo, NAKANO, Masuo, FUJINO, Yasuhiko   +2 more
openaire   +2 more sources

Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11796-11807, December 2026.
ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang, Kevin Cho, Max C. Petersen, Kai E. Jones, Gary J. Patti, Janet B. McGill, Samantha A. DiGruccio   +6 more
wiley   +1 more source