Results 231 to 240 of about 33,232 (287)

Targeted inhibition of hepatic de novo ceramide synthesis ameliorates MASH. [PDF]

Sci Adv
Yu X, Huang C, Evers M, Liu J, Ting HJ, Zhang S, Chong SY, Tan MS, Wang S, Sayed N, Gao L, Muthiah MD, Soon GST, Wee A, Chow EK, Soh NJH, Pastorin G, Yu VC, Liu B, Dan YY, Torta F, Schiffelers R, Storm G, Wang JW.   +23 more
europepmc   +1 more source

Acyl‐CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark, R. Petersen, P. M. M. Ruppert, E. S. Jul, T. K. Doktor, R. Nielsen, J. F. Kappel, S. Larsen, J. W. Kornfeld, S. Mandrup, B. S. Andresen, J. Havelund, D. Neess, N. J. Færgeman   +13 more
wiley   +1 more source

Comment on "Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure". [PDF]

Int J Surg
Xiang Q, Lin W, Wang J.
europepmc   +1 more source

MSC‐Derived Secretome and Exosomes in Dermatology: Mechanisms, Therapeutic Opportunities, and Scientific Challenges—A Narrative Review

International Journal of Dermatology, Volume 65, Issue 2, Page 257-272, February 2026.
ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari, Reinaldo Falavigna Tovo, Daniela Franco Bueno   +2 more
wiley   +1 more source

Unlocking the therapeutic potential of sphingolipids in wound healing: from molecular mechanisms to clinical applications. [PDF]

Int J Surg
Sujie X, Xinran D, Yixu L, Wei Z, Shuyuan X, Yifan L, Yuntao Y, Bingnan L, Xirui T, Xinya G, Runzhi H, Shizhao J, Zhaofan X.   +12 more
europepmc   +1 more source

Unveiling the Therapeutic Potential of “Taikong Blue” Lavender Essential Oil and Its Key Compounds in Skin Problems via Network Pharmacology and In Vitro Validation

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Taikong Blue Lavender Essential Oil (TLEO) is derived from a proprietary space‐bred cultivar of Lavandula angustifolia and cultivated under pristine conditions in Xinjiang, China. TLEO has long been used by regional people to treat various skin disorders such as hyperpigmentation, trans‐epidermal water loss, collagen degradation ...
Fei Liu, Yingyu Zhang, Minhazul Abedin, Jingyi Song, Suzhen Yang, Hongxiang Lou, Xixi Dou, Junsong Xiao, Hua Wu   +8 more
wiley   +1 more source

Fasting the mitochondria to prevent neurodegeneration: the role of ceramides. [PDF]

Front Neurosci
Valenzuela-Ahumada LA, Mercado-Gómez OF, Viveros-Contreras R, Guevara-Guzmán R, Camacho-Morales A.   +4 more
europepmc   +1 more source

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo

Veterinary Dermatology, Volume 37, Issue 1, Page 140-147, February 2026.
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka, Elisabeta Samuel (Badulescu), Manolis K. Chatzis, Manolis N. Saridomichelakis   +3 more
wiley   +1 more source

Skin Barrier Repair and Nursing Care in Patients with Atopic Dermatitis: A Narrative Review. [PDF]

Int J Gen Med
Chen X.
europepmc   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou, Yitong Lu, Zhaobao Wang, Xiaoqian Du, Bei Jiang, Qiuhui Xuan   +5 more
wiley   +1 more source