Cerebellar integrity in the amyotrophic lateral sclerosis-frontotemporal dementia continuum. [PDF]
PLoS ONE, 2014 Amyotrophic lateral sclerosis (ALS) and behavioural variant frontotemporal dementia (bvFTD) are multisystem neurodegenerative disorders that manifest overlapping cognitive, neuropsychiatric and motor features.
Rachel H Tan +7 more
doaj +14 more sources
Regional cerebellar atrophy related to disability and cognitive progression in multiple sclerosis [PDF]
NeuroImage: ClinicalObjective: The implications of cerebellar pathology on clinical disease progression in multiple sclerosis (MS) remain unclear. This study investigated regional cerebellar atrophy related to physical disability and cognitive impairment progression ...
Myrte Strik +8 more
doaj +2 more sources
Mapping the path to degeneration: How lesion location predicts post-stroke cerebellar atrophy [PDF]
NeuroImage: ClinicalIntroduction: Stroke can lead to neurological changes beyond the initial lesion site, including post-stroke crossed-cerebellar degeneration. While traditional methods typically rely on total lesion volume to assess remote effects, the spatial ...
Makayla Gibson +6 more
doaj +2 more sources
Incidence and Characteristics of Cerebellar Atrophy/Volume Loss in Children with Confirmed Diagnosis of Tuberous Sclerosis Complex [PDF]
ChildrenObjectives: The goal of our study was to determine the incidence of cerebellar atrophy, assess the imaging findings in the posterior fossa and determine the incidence of hippocampal sclerosis in a cohort of pediatric patients with confirmed tuberous ...
Livja Mertiri +5 more
doaj +2 more sources
Cortical, subcortical, and cerebellar atrophy and cognition deficits in Metropolitan Mexico City teens and young adults exposed to fine particulate matter (PM2.5) - neurodegeneration is in progress [PDF]
Frontiers in NeurologyExposure to environmental fine particulate matter (PM2.5), ultrafine PM (UFPM) and nanoparticles (NPs) are associated with accumulation of amyloid-β1–42 peptides, phosphorylated-Tau, alpha-synuclein and transactive response DNA binding-protein-43 ...
Lilian Calderón-Garcidueñas +10 more
doaj +2 more sources
Neuroimaging of Pediatric Cerebellum in Inherited Neurodegenerative Diseases
Applied Sciences, 2021 In the study of cerebellar degenerative diseases, morphologic imaging (computed tomography, CT and magnetic resonance imaging, MRI) is the most common examination.
Luisa Chiapparini, Marco Moscatelli
doaj +1 more source
Channelopathies Are a Frequent Cause of Genetic Ataxias Associated with Cerebellar Atrophy [PDF]
Movement Disorders Clinical Practice, 2020 Taila Hartley +2 more
exaly +2 more sources
Genetic ablation of PLA2G6 in mice leads to cerebellar atrophy characterized by Purkinje cell loss and glial cell activation. [PDF]
PLoS ONE, 2011 Infantile neuroaxonal dystrophy (INAD) is a progressive, autosomal recessive neurodegenerative disease characterized by axonal dystrophy, abnormal iron deposition and cerebellar atrophy.
Zhengshan Zhao +5 more
doaj +1 more source
Cerebellar cognitive affective syndrome due to cerebellar atrophy: case report
Geriatrics, Gerontology and Aging, 2022 Cerebellar atrophy is a rare and challenging disease with few descriptions in the medical literature. Motor impairment is mild, but behavioral and linguistic alterations stand out, in what is known as the cerebellar cognitive affective syndrome secondary
Einstein Francisco Camargos +3 more
doaj +1 more source
Frontiers in Neuroscience, 2023 Subcortical vascular mild cognitive impairment (svMCI) is associated with structural and functional changes in the cerebral cortex affecting major brain networks.
Alaka Acharya +5 more
doaj +1 more source