Results 21 to 30 of about 47,175 (263)

Hypocupremia: A Possible Association with Late Cortical Cerebellar Atrophy

Tremor and Other Hyperkinetic Movements, 2014
Background: We report a patient, diagnosed with late cortical cerebellar atrophy, who had persistent low serum copper levels.Case report: A 48-year-old male developed progressive difficulty with balance, frequent falls, and dysarthric speech, which ...
Shivam O. Mittal, Duarte G. Machado
doaj   +1 more source

Cerebellar integrity in the amyotrophic lateral sclerosis-frontotemporal dementia continuum. [PDF]

PLoS ONE, 2014
Amyotrophic lateral sclerosis (ALS) and behavioural variant frontotemporal dementia (bvFTD) are multisystem neurodegenerative disorders that manifest overlapping cognitive, neuropsychiatric and motor features.
Rachel H Tan, Emma Devenney, Carol Dobson-Stone, John B Kwok, John R Hodges, Matthew C Kiernan, Glenda M Halliday, Michael Hornberger   +7 more
doaj   +1 more source

Cerebellar Atrophy in Epileptic Patients [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1988
ABSTRACT:High-resolution CT scans of the brain and posterior fossa were performed on 106 phenytoin (PHT)- treated epileptics, 28 de novo epileptics and 43 control subjects. A higher incidence of cerebellar and brainstem (CBS) atrophy was observed in chronic PHT- or PHT+ phenobarbital-treated epileptics compared to the two other groups.
M I, Botez, E, Attig, J L, Vézina
openaire   +2 more sources

Morphological changes in the cerebellum during aging: evidence from convolutional neural networks and shape analysis

Frontiers in Aging Neuroscience
The morphology and function of the cerebellum are associated with various developmental disorders and healthy aging. Changes in cerebellar morphology during the aging process have been extensively investigated, with most studies focusing on changes in ...
Yu Wang, Yu Wang, Ye Teng, Ye Teng, Tianci Liu, Tianci Liu, Yuchun Tang, Yuchun Tang, Wenjia Liang, Wenjia Liang, Wenjun Wang, Wenjun Wang, Zhuoran Li, Qing Xia, Qing Xia, Feifei Xu, Feifei Xu, Shuwei Liu, Shuwei Liu   +18 more
doaj   +1 more source

Linking the cerebellum posterior lobules atrophy to multiple system atrophy cognitive impairment

Neurobiology of Disease
Background: Cognitive impairments in multiple system atrophy (MSA) are linked to cerebellar dysfunction, but the role of specific posterior cerebellar lobules in domain-specific deficits remains unclear.
Huaguang Yang, Yunfei Zha, Weiyin Vivian Liu, Zhi Wen, Gonghao Ling, Di Zhang, Wenbing Yang   +6 more
doaj   +1 more source

A Clinical-Based Diagnostic Approach to Cerebellar Atrophy in Children

Applied Sciences, 2021
Background: Cerebellar atrophy is a neuroradiological definition that categorizes conditions heterogeneous for clinical findings, disease course, and genetic defect.
Claudia Ciaccio, Chiara Pantaleoni, Franco Taroni, Daniela Di Bella, Stefania Magri, Eleonora Lamantea, Daniele Ghezzi, Enza Maria Valente, Vincenzo Nigro, Stefano D’Arrigo   +9 more
doaj   +1 more source

Hipoplasias cerebelosas.

Acta Médica Portuguesa, 2010
Cerebellar hypoplasias are cerebellar malformations with small but completely formed cerebellum. They can be divided in focal and in diffuse or generalized.
Marta Maia Safronova, Clara Barbot, Jorge Resende Pereira   +2 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Cerebellar Atrophy and Autism

Pediatric Neurology Briefs, 1987
Magnetic resonance imaging scans (MRI) were obtained for 14 autistic patients, aged 4 to 19 yrs, diagnosed by DSM-III criteria at the Univ of Iowa Hospitals, Iowa City, and were compared to a control group.
J Gordon Millichap
doaj   +1 more source